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A5UU40 (GSA_ROSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase

Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:hemL
Ordered Locus Names:RoseRS_1753
OrganismRoseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP]
Taxonomic identifier357808 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeRoseiflexus

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processChlorophyll biosynthesis
Porphyrin biosynthesis
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processchlorophyll biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

protoporphyrinogen IX biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutamate-1-semialdehyde 2,1-aminomutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

transaminase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375
PRO_1000201032

Amino acid modifications

Modified residue2671N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A5UU40 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 5B88171A32907A7A

FASTA42744,447
        10         20         30         40         50         60 
MKTTRSESLF AEAQSLFPGG VNSPVRAFRA VGGTPRFIAR GEGALIFDVD GNRYIDYVLS 

        70         80         90        100        110        120 
WGPLIAGHTH PDVVAAIAEQ AARGTSFGAP TELESELARL IIQAMPAVEM VRFVSSGTEA 

       130        140        150        160        170        180 
AMSALRLARA ATRRDKVIKF AGCYHGHFDG FLVQAGSGVA TLGLPDSPGV TAATAAGTLT 

       190        200        210        220        230        240 
APYNDLDAVE ALLKANPGEV AAIAVEPVAG NMGLVLPQPG FLAGLRRLAD EHGALLIFDE 

       250        260        270        280        290        300 
VMTGFRVAYG GAQGRYGITP DLTCLGKVIG GGLPAAAYGG RRELMELIAP AGPVYQAGTL 

       310        320        330        340        350        360 
SGNPLAMAAG IATLRIIGAP GVFERLEQAT AALCAGFERA AADADIPLRA AYAGSMWGFF 

       370        380        390        400        410        420 
FTGDPVVDYA SAKKADTRRY ARFFHAMLER GVYLAPAQFE AAFVSLAHSD ALIQETIAAA 


ADALRSL 

« Hide

References

[1]"Complete sequence of Roseiflexus sp. RS-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RS-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000686 Genomic DNA. Translation: ABQ90143.1.
RefSeqYP_001276093.1. NC_009523.1.

3D structure databases

ProteinModelPortalA5UU40.
SMRA5UU40. Positions 1-424.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357808.RoseRS_1753.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ90143; ABQ90143; RoseRS_1753.
GeneID5208710.
KEGGrrs:RoseRS_1753.
PATRIC23351718. VBIRosSp109359_1917.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0001.
HOGENOMHOG000020210.
KOK01845.
OMARAIKPYP.
OrthoDBEOG6QVRHN.

Enzyme and pathway databases

BioCycRSP357808:GH5Z-1777-MONOMER.
UniPathwayUPA00251; UER00317.
UPA00668.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPMF_00375. HemL_aminotrans_3.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_ROSS1
AccessionPrimary (citable) accession number: A5UU40
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways