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A5URE6 (A5URE6_ROSS1) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:RoseRS_0785 EMBL ABQ89199.1
OrganismRoseiflexus sp. (strain RS-1) [Complete proteome] [HAMAP] EMBL ABQ89199.1
Taxonomic identifier357808 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeRoseiflexus

Protein attributes

Sequence length453 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
A5URE6 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 10E9422F8AB8C960

FASTA45350,046
        10         20         30         40         50         60 
MTTTRNRAPE GDAISIRNGR LYVPDMPIIP YVEGDGTGPD IWRASVRVFD AAVERAYGGR 

        70         80         90        100        110        120 
RKLMWYEVLA GEKAFNLTGN WLPDETVEAF RQYLVGIKGP LTTPVGRGIR SLNVALRQLL 

       130        140        150        160        170        180 
DLYVCLRPVR YFQGVPSPVK RPELVDMVIF RENTEDIYAG IEYAAGTPEA QKVLDFLRTT 

       190        200        210        220        230        240 
FPKDFEKIRF GTAEKAREFL SLLGNGDGEG AVEVGIGIKP VSRLGTERLV AAAIQYAITH 

       250        260        270        280        290        300 
RRRSVTFVHK GNIMKFTEGA FRDWGYALAE RVFGEHVYTW AQWERTKAEK GEAAANAEQR 

       310        320        330        340        350        360 
EALAAGAILI KDAIADITLQ QVLTRPEEFD VIATLNLNGD YLSDALAAQV GGIGIAPGGN 

       370        380        390        400        410        420 
INYITGHAIF EATHGTAPKY ANLDRVNPGS VILSGDMMLR YMGWTEAADL IIRALEKTIA 

       430        440        450 
QKIVTYDFAR LMTGAKEVKT SQFADAMIAN MDE 

« Hide

References

[1]"Complete sequence of Roseiflexus sp. RS-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RS-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000686 Genomic DNA. Translation: ABQ89199.1.
RefSeqYP_001275149.1. NC_009523.1.

3D structure databases

ProteinModelPortalA5URE6.
SMRA5URE6. Positions 10-452.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357808.RoseRS_0785.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ89199; ABQ89199; RoseRS_0785.
GeneID5207728.
KEGGrrs:RoseRS_0785.
PATRIC23349567. VBIRosSp109359_0855.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycRSP357808:GH5Z-795-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5URE6_ROSS1
AccessionPrimary (citable) accession number: A5URE6
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)