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A5UMZ9 (A5UMZ9_METS3) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase HAMAP MF_00197
Short name=DAP epimerase HAMAP MF_00197
EC=5.1.1.7 HAMAP MF_00197
Gene names
Name:dapF HAMAP MF_00197
Ordered Locus Names:Msm_1372
OrganismMethanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) [Complete proteome] [HAMAP] EMBL ABQ87577.1
Taxonomic identifier420247 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanobrevibacter

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family. HAMAP MF_00197

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis HAMAP MF_00197
   Cellular componentCytoplasm HAMAP MF_00197
   Molecular functionIsomerase HAMAP MF_00197 EMBL ABQ87577.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site791 By similarity HAMAP MF_00197
Active site2281 By similarity HAMAP MF_00197

Sequences

Sequence LengthMass (Da)Tools
A5UMZ9 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 3D11536782EFB41F

FASTA28631,303
        10         20         30         40         50         60 
MDLKGLKFSK MHGIGNDFPI INESAGEVIP EADKAEACRF LCHRHFGVGG DGVLFVTPSD 

        70         80         90        100        110        120 
VADIGYRMFN PDGSEAEMCG NGIRCFGDFV YRKGILKQEK MTVETKSGIK TIEITLENDE 

       130        140        150        160        170        180 
PVLFKVDMGT STFKTPEIPM ASDMDEFLDS PLEVLDTTFN TTAISVGNPH AIIFVDNIDE 

       190        200        210        220        230        240 
IDIDKYGPAI ETHEVFPEKI NVHFVEVISK NEGKMLTWER GAGVTLACGT GATSTAISGF 

       250        260        270        280 
KLGLFDSEVL LHLPGGDLKF NVYEKEEELG AFMEGPAQLV FDGEIQ

« Hide

References

[1]"Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut."
Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B., Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.
Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007) [PubMed: 17563350] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000678 Genomic DNA. Translation: ABQ87577.1.
RefSeqYP_001273945.1. NC_009515.1.

3D structure databases

ProteinModelPortalA5UMZ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5UMZ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5216840.
GenomeReviewsGene locus Msm_1372 in contig CP000678_GR.
KEGGmsi:Msm_1372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG07445.
HOGENOMHBG399442.
OMAFMTGPAT.
ProtClustDBPRK00450.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5UMZ9_METS3
AccessionPrimary (citable) accession number: A5UMZ9
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: November 16, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info