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A5UMC0 (A5UMC0_METS3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134
Gene names
Name:trpC HAMAP MF_00134
Ordered Locus Names:Msm_1143
OrganismMethanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) [Complete proteome] [HAMAP] EMBL ABQ87348.1
Taxonomic identifier420247 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanobrevibacter

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134

Sequence similarities

Belongs to the TrpC family. HAMAP MF_00134

Sequences

Sequence LengthMass (Da)Tools
A5UMC0 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 17736FF24D24701B

FASTA25828,980
        10         20         30         40         50         60 
MLDKIVEKTK ERVSENKKVN SLDRLKYKIL NIDVKFNYPF KKALSSDDIA IIAEVKKASP 

        70         80         90        100        110        120 
SKGLIAENFD YVNIAKEYEA AGASAISVLT EPYFFQGSDD YLKKIAKNVK IPVLRKDFVV 

       130        140        150        160        170        180 
DEYMIYEAKL LGASAVLLIA AILSDEQLEQ YLTITRVLGM SAIVEAHDEN EIKRAIDAGA 

       190        200        210        220        230        240 
DIVGVNNRNL KDFSVDIENS IRLRRCVDED IIFISESGIK TKEDIARLKE NNVDAVLIGE 

       250 
TLMKSPDKKV MIRELKNG

« Hide

References

[1]"Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut."
Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B., Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.
Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007) [PubMed: 17563350] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000678 Genomic DNA. Translation: ABQ87348.1.
RefSeqYP_001273716.1. NC_009515.1.

3D structure databases

ProteinModelPortalA5UMC0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5UMC0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5215729.
GenomeReviewsGene locus Msm_1143 in contig CP000678_GR.
KEGGmsi:Msm_1143.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04622.
HOGENOMHBG540956.
OMAMRKDDVT.
ProtClustDBPRK00278.

Family and domain databases

HAMAPMF_00134_A. IGPS_A.
[Tree]
MF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5UMC0_METS3
AccessionPrimary (citable) accession number: A5UMC0
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info