A5UL80 (RNP1_METS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	Msm_0753

Organism

Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) [Complete proteome] [HAMAP]

Taxonomic identifier

420247 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanobrevibacter

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_1000046615

Sequences

	Sequence		Length	Mass (Da)
	A5UL80 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: EEB468151514A9DC	FASTA	92	10,402
	10 20 30 40 50 60 MITVNNLVHH EFIGLSVSVT SVSNESLRLK GTVIDETKNT IKIEVDDNVE KIIPKKGSIF 70 80 90 VFELPTGEKV EINGNILSIR PEDRIKKRFK KI

References

[1]

"Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut." Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B., Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007) [PubMed: 17563350] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PS / ATCC 35061 / DSM 861.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000678 Genomic DNA. Translation: ABQ86958.1.
RefSeq	YP_001273326.1. NC_009515.1.
3D structure databases
ProteinModelPortal	A5UL80.
ModBase	Search...
Protein-protein interaction databases
STRING	A5UL80.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5215855.
GenomeReviews	Gene locus Msm_0753 in contig CP000678_GR.
KEGG	msi:Msm_0753.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG12604.
HOGENOM	HBG704950.
OMA	ISTKGRV.
Family and domain databases
HAMAP	MF_00754. RNase_P_1. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
KO	K03538.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_METS3

Accession

Primary (citable) accession number: A5UL80

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 10, 2007
Last modified:	November 16, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program