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Reviewed, UniProtKB/Swiss-Prot A5UKY4 (APGM_METS3)

Last modified November 3, 2009. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1
Gene names
Name: apgM
Ordered Locus Names: Msm_0657
OrganismMethanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) [Complete proteome] [HAMAP]
Taxonomic identifier420247 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanobrevibacter

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Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

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Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4124122,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402
PRO_1000087365

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Sequences

Sequence LengthMass (Da)Tools
A5UKY4-1 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: CF998AE7A7953467

FASTA41244,903
        10         20         30         40         50         60 
MKGIVLVMDG MGDRPLKEFD NQTPLQAANT PNMDEMAKNG ITGIMDSIAP GIIPGSDTAH 

        70         80         90        100        110        120 
LSILGYDPYE VYTGRGPFEA AGVGVDVIPG DIAFRCNFST ADENGIVTDR RAGRIREGTH 

       130        140        150        160        170        180 
EIVEVLNTMV LEDYPDIKII FKESTGHRAV LVLRGEGLSD KVSDADPKVE GNKPKEVIPL 

       190        200        210        220        230        240 
DDSVEAKKTA DILNKLVVKS YEMIKDHPVN LERIENNEPP ANIIIPRGAG EVPVVEALND 

       250        260        270        280        290        300 
KYEVNSACIA ETGLIMGIGR FAGMDIIEME DVTGGIDTNL ENIRDTIIDQ VKNSDHDFFL 

       310        320        330        340        350        360 
INIDGADEAG HDGQAVEKRD FIEKVDRVVM SELKKLEDVY IFLTADHSTP ISVLNHSGDP 

       370        380        390        400        410 
VPVIITGPEV RVDDVCEYSE VAVAKGGLCR IRGADVMNIM MDLMNYAHKF GA

« Hide

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References

[1]"Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut."
Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B., Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.
Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007) [PubMed: 17563350] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000678 Genomic DNA. Translation: ABQ86862.1.
RefSeqYP_001273230.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5UKY4.

Genome annotation databases

GeneID5216097.
GenomeReviewsGene locus Msm_0657 in contig CP000678_GR.
KEGGmsi:Msm_0657.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAITGDHST.

Family and domain databases

HAMAPMF_01402.
[Tree]
InterProIPR004456. APGAM_arc.
IPR019304. bisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
ProDomPD004704. APGAM_DeoB. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00306. apgM. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameAPGM_METS3
AccessionPrimary (citable) accession number: A5UKY4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 10, 2007
Last modified: November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents