Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5UIW8 (ACKA_HAEIG) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:CGSHiGG_09740
OrganismHaemophilus influenzae (strain PittGG) [Complete proteome] [HAMAP]
Taxonomic identifier374931 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Acetate kinase HAMAP MF_00020
PRO_1000002235

Sequences

Sequence LengthMass (Da)Tools
A5UIW8 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 9D39D84805EB4236

FASTA40143,754
        10         20         30         40         50         60 
MSKLVLILNC GSSSLKFAIL DPATGEEKLS GLAEAFFLPE ARIKWKLNGE KGNADLGAGA 

        70         80         90        100        110        120 
AHTEALNFIA SNILNDELKN SIAAIGHRIV HGGEKYTQSV IVTDEVVKGI EDAAQFAPLH 

       130        140        150        160        170        180 
NPAHLIGIRE AFKAFPHLKD KNVVVFDTAF HQTMPEEAFL YALPYSLYKE HGVRRYGAHG 

       190        200        210        220        230        240 
TSHYFVSREV AEYVGKPADQ VNAIICHLGN GGSVSVVRNG QCIDTSMGLT PLEGLVMGTR 

       250        260        270        280        290        300 
CGDIDPAIVF YLYKTLGMSM DQIEETLVKK SGLLGLTEVT SDCRYAEDNY DDESKPETKR 

       310        320        330        340        350        360 
ALNVYSYRLA KYIGAYMAVL GDDHLDAIAF TGGIGENSAH VRELALNHLK LFGIKIDHER 

       370        380        390        400 
NLATRFGKDG VITTDDSAFK AIVLPTNEEL VIAQDTAKLC F

« Hide

References

[1]"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains."
Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D.
Genome Biol. 8:R103.1-R103.18(2007) [PubMed: 17550610] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PittGG.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000672 Genomic DNA. Translation: ABR00724.1.
RefSeqYP_001293107.1. NC_009567.1.

3D structure databases

ProteinModelPortalA5UIW8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5UIW8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5227771.
GenomeReviewsGene locus CGSHiGG_09740 in contig CP000672_GR.
KEGGhiq:CGSHiGG_09740.
PATRIC20188247. VBIHaeInf102487_1968.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMAIVFHLHD.
ProtClustDBPRK00180.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_HAEIG
AccessionPrimary (citable) accession number: A5UIW8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents