A5UHH2 (GLPB_HAEIG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	CGSHiGG_06720

Organism

Haemophilus influenzae (strain PittGG) [Complete proteome] [HAMAP]

Taxonomic identifier

374931 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753
Cofactor	FMN By similarity. HAMAP-Rule MF_00753
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753
Subunit structure	Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycerol catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753		PRO_1000046605

Sequences

	Sequence		Length	Mass (Da)
	A5UHH2 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: FEAA12F0EA8B0BFC	FASTA	432	47,251
	10 20 30 40 50 60 MNFDVAIIGG GLAGLTCGIA IQQRGKRCVI INNGQAAIDF ASGSLDLLSR MPSTSNGESR 70 80 90 100 110 120 TVENLKENIT ALRNELPAHP YSLLGAEKVL AKAQDFERLA NELHLDLIGS TEKNHWRVTG 130 140 150 160 170 180 LGSLRGAWLS PNSVPTVQGN ELFPHKRIAV LGIEGYHDFQ PQLLAANLVL NPQFEHCEVT 190 200 210 220 230 240 SGFLNIPQLD ELRKNAREFR SVNISQLLEH KLAFKDLVKE IIESSQGAEA VFLPACFGLE 250 260 270 280 290 300 NQEFMTALRD ATKLALFELP TLPPSLLGMR QRIQLRHKFE SLGGLMINGD SALNATFEGN 310 320 330 340 350 360 KVRCINTRLL EDEEITADNF VLASGSFFSK GLISEFDKIY EPVFESDIIG VEGFNQKDRF 370 380 390 400 410 420 TWTVHRFAHP QPYQSAGVAI NAQCQVQKCG QFLTNLYAVG NVIGGFNALE LGCGSGVAVV 430 TALAVADEIL AK

References

[1]

"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains." Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D. Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PittGG.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000672 Genomic DNA. Translation: ABR00228.1.
RefSeq	YP_001292611.1. NC_009567.1.
3D structure databases
ProteinModelPortal	A5UHH2.
ModBase	Search...
Protein-protein interaction databases
STRING	374931.CGSHiGG_06720.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR00228; ABR00228; CGSHiGG_06720.
GeneID	5226632.
KEGG	hiq:CGSHiGG_06720.
PATRIC	20186973. VBIHaeInf102487_1355.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HOG000278489.
KO	K00112.
OMA	FRSVNIS.
ProtClustDB	PRK05329.
Enzyme and pathway databases
BioCyc	HINF374931:GJA4-1169-MONOMER.
UniPathway	UPA00618; UER00673.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB.
InterPro	IPR003953. FAD_bind_dom. IPR009158. G3P_DH_GlpB_su. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_HAEIG

Accession

Primary (citable) accession number: A5UHH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 10, 2007
Last modified:	May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program