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A5UH23 (DEOD_HAEIG) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:CGSHiGG_05840
OrganismHaemophilus influenzae (strain PittGG) [Complete proteome] [HAMAP]
Taxonomic identifier374931 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_1000069632

Sequences

Sequence LengthMass (Da)Tools
A5UH23 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 0347D072F2B9D661

FASTA23825,872
        10         20         30         40         50         60 
MTPHINAPEG AFADVVLMPG DPLRAKYIAE TFLQDVVEVT NVRNMLGFTG TYKGRKISIM 

        70         80         90        100        110        120 
GHGMGIPSCS IYAKELITEY GVKKIIRVGS CGTVRMDVKV RDVIIGLGAC TDSKVNRIRF 

       130        140        150        160        170        180 
KDNDFAAIAD FDMAQAAVQA AKAKGKAVRV GNLFSADLFY TPDVEMFDVM EKYGILGVEM 

       190        200        210        220        230 
EAAGIYGVAA EYGAKALTIC TVSDHIRTHE QTTAEERQLT FNDMIEIALD SVLIGDAQ 

« Hide

References

[1]"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains."
Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D.
Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PittGG.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000672 Genomic DNA. Translation: ABR00079.1.
RefSeqYP_001292462.1. NC_009567.1.

3D structure databases

ProteinModelPortalA5UH23.
SMRA5UH23. Positions 2-236.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING374931.CGSHiGG_05840.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR00079; ABR00079; CGSHiGG_05840.
GeneID5226481.
KEGGhiq:CGSHiGG_05840.
PATRIC20186592. VBIHaeInf102487_1176.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0813.
HOGENOMHOG000274896.
KOK03784.
OMASFETHAF.
OrthoDBEOG6BKJC5.
ProtClustDBPRK05819.

Enzyme and pathway databases

BioCycHINF374931:GJA4-1006-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_HAEIG
AccessionPrimary (citable) accession number: A5UH23
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families