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Protein

Uronate isomerase

Gene

uxaC

Organism
Haemophilus influenzae (strain PittGG)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciHINF374931:GJA4-460-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:CGSHiGG_02740
OrganismiHaemophilus influenzae (strain PittGG)
Taxonomic identifieri374931 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000001990 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Uronate isomerasePRO_1000044769Add
BLAST

Proteomic databases

PRIDEiA5UFL7.

Structurei

3D structure databases

ProteinModelPortaliA5UFL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A5UFL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSFMDENFL LSTDTAKILY HDYAKNKPIF DYHCHLNPRE VAENRQFNDL
60 70 80 90 100
AEIWLEGDHY KWRALRTAGV PEELITGKAT NYQKYLAWAK TVPLCIGNPI
110 120 130 140 150
YHWTHLELRR PFGITNMLFN PQNAEKIWHQ CNEMLQQPEF SARGIMQKMN
160 170 180 190 200
VKLVGTTDDP IDSLQYHQAI KNDESFDIDV VPSWRPDKVF KIELPQFNDY
210 220 230 240 250
LVQLSEIADV DIYTFADLKK ALLKRLEYFD AQGCKSADHG MEIVRFSAIP
260 270 280 290 300
DESVLNSILQ KRLQNQPLLE EEVAQFSTAI LVWLASEYCK RHWVMQMHIG
310 320 330 340 350
AIRNNNSRMF ALLGADSGFD SIGDRAYAYP LSRLLDAMDK ENQLPKTILY
360 370 380 390 400
CLNPRDNEMI ASMIGNFQGD GIAGKIQFGS GWWFNDQKDG MERQLQQLSQ
410 420 430 440 450
LGLLSQFVGM LTDSRSFLSY TRHEYFRRIL CEMIGGWVEK GEAPNDISLL
460
GKMIEDICFN NAKNYFK
Length:467
Mass (Da):54,082
Last modified:July 10, 2007 - v1
Checksum:i79AC1FE7561D2C2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000672 Genomic DNA. Translation: ABQ99572.1.

Genome annotation databases

EnsemblBacteriaiABQ99572; ABQ99572; CGSHiGG_02740.
KEGGihiq:CGSHiGG_02740.
PATRICi20185267. VBIHaeInf102487_0552.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000672 Genomic DNA. Translation: ABQ99572.1.

3D structure databases

ProteinModelPortaliA5UFL7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA5UFL7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ99572; ABQ99572; CGSHiGG_02740.
KEGGihiq:CGSHiGG_02740.
PATRICi20185267. VBIHaeInf102487_0552.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciHINF374931:GJA4-460-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains."
    Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D.
    Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PittGG.

Entry informationi

Entry nameiUXAC_HAEIG
AccessioniPrimary (citable) accession number: A5UFL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: November 11, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.