Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A5UEJ2 (GLGB_HAEIG) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:CGSHiGG_00440
OrganismHaemophilus influenzae (strain PittGG) [Complete proteome] [HAMAP]
Taxonomic identifier374931 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length730 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7307301,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_1000044980

Sites

Active site4051Nucleophile By similarity
Active site4581Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A5UEJ2 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 98AC5D5D0F8E1A51

FASTA73083,844
        10         20         30         40         50         60 
MTTAVTQAII DGFFDASNGD PFATLGMHET EQGIEIRTLL PDANRMVVIE RESGKEITEL 

        70         80         90        100        110        120 
DCVDERGFFV GVIPNCRQFF AYQLQVFWGN EAQIIEDPYR FHPMIDDLEQ WLLSEGSMLR 

       130        140        150        160        170        180 
PYEVLGAHFM ECDGVSGVNF RLWAPNARRV SIVGDFNYWD GRRHPMRFHS KSGVWELFLP 

       190        200        210        220        230        240 
KASLGQLYKF ELIDCHGNLR LKADPFAFSS QLRPDTASQV SALPNVVEMT EARKKANQGN 

       250        260        270        280        290        300 
QPISIYEVHL GSWRRNLENN FWLDYDQIAD ELIPYVKEMG FTHIEFLPLS EFPFDGSWGY 

       310        320        330        340        350        360 
QPLGLYSPTS RFGSPEAFSR LVKRAHEAGI NVILDWVPGH FPSDTHGLVA FDGTALYEHE 

       370        380        390        400        410        420 
DPREGYHQDW NTLIYNYGRN EVKNFLSSNA LYWLERFGVD GIRVDAVASM IYRDYSRVEG 

       430        440        450        460        470        480 
EWIPNQYGGR ENLEAIEFLK HTNWKIHSEM AGAISIAEES TSFAGVTHPS ENGGLGFNFK 

       490        500        510        520        530        540 
WNMGWMNDTL AYMKLDPIYR QYHHNKMTFG MVYQYSENFV LPLSHDEVVH GKYSLLGKMP 

       550        560        570        580        590        600 
GDTWQKFANL RAYYGYMWGY PGKKLLFMGN EFAQGREWNH EESLDWFLLD ENIDGGWHKG 

       610        620        630        640        650        660 
VLKLVKDLNQ IYQKNRPLFE LDNSPEGFDW LVVDDAANSV FAFERRSSNG ERIIVVSNFT 

       670        680        690        700        710        720 
PVPRHDYRIG VNIVGEYEEI LNTDSMYYQG SNVGNFGCVA SENIESHGRE NSISVSIPPL 

       730 
ATVYLRLKAK 

« Hide

References

[1]"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains."
Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D.
Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PittGG.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000672 Genomic DNA. Translation: ABQ99197.1.
RefSeqYP_001291581.1. NC_009567.1.

3D structure databases

ProteinModelPortalA5UEJ2.
SMRA5UEJ2. Positions 119-730.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING374931.CGSHiGG_00440.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ99197; ABQ99197; CGSHiGG_00440.
GeneID5227881.
KEGGhiq:CGSHiGG_00440.
PATRIC20184315. VBIHaeInf102487_0089.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycHINF374931:GJA4-72-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_HAEIG
AccessionPrimary (citable) accession number: A5UEJ2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries