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A5UEJ2

- GLGB_HAEIG

UniProt

A5UEJ2 - GLGB_HAEIG

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Protein
1,4-alpha-glucan branching enzyme GlgB
Gene
glgB, CGSHiGG_00440
Organism
Haemophilus influenzae (strain PittGG)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei405 – 4051Nucleophile By similarity
Active sitei458 – 4581Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciHINF374931:GJA4-72-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name:
BE
Gene namesi
Name:glgB
Ordered Locus Names:CGSHiGG_00440
OrganismiHaemophilus influenzae (strain PittGG)
Taxonomic identifieri374931 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000001990: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7307301,4-alpha-glucan branching enzyme GlgBUniRule annotation
PRO_1000044980Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi374931.CGSHiGG_00440.

Structurei

3D structure databases

ProteinModelPortaliA5UEJ2.
SMRiA5UEJ2. Positions 119-730.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiAKLLFMG.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

A5UEJ2-1 [UniParc]FASTAAdd to Basket

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MTTAVTQAII DGFFDASNGD PFATLGMHET EQGIEIRTLL PDANRMVVIE    50
RESGKEITEL DCVDERGFFV GVIPNCRQFF AYQLQVFWGN EAQIIEDPYR 100
FHPMIDDLEQ WLLSEGSMLR PYEVLGAHFM ECDGVSGVNF RLWAPNARRV 150
SIVGDFNYWD GRRHPMRFHS KSGVWELFLP KASLGQLYKF ELIDCHGNLR 200
LKADPFAFSS QLRPDTASQV SALPNVVEMT EARKKANQGN QPISIYEVHL 250
GSWRRNLENN FWLDYDQIAD ELIPYVKEMG FTHIEFLPLS EFPFDGSWGY 300
QPLGLYSPTS RFGSPEAFSR LVKRAHEAGI NVILDWVPGH FPSDTHGLVA 350
FDGTALYEHE DPREGYHQDW NTLIYNYGRN EVKNFLSSNA LYWLERFGVD 400
GIRVDAVASM IYRDYSRVEG EWIPNQYGGR ENLEAIEFLK HTNWKIHSEM 450
AGAISIAEES TSFAGVTHPS ENGGLGFNFK WNMGWMNDTL AYMKLDPIYR 500
QYHHNKMTFG MVYQYSENFV LPLSHDEVVH GKYSLLGKMP GDTWQKFANL 550
RAYYGYMWGY PGKKLLFMGN EFAQGREWNH EESLDWFLLD ENIDGGWHKG 600
VLKLVKDLNQ IYQKNRPLFE LDNSPEGFDW LVVDDAANSV FAFERRSSNG 650
ERIIVVSNFT PVPRHDYRIG VNIVGEYEEI LNTDSMYYQG SNVGNFGCVA 700
SENIESHGRE NSISVSIPPL ATVYLRLKAK 730
Length:730
Mass (Da):83,844
Last modified:July 10, 2007 - v1
Checksum:i98AC5D5D0F8E1A51
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000672 Genomic DNA. Translation: ABQ99197.1.
RefSeqiWP_011962031.1. NC_009567.1.
YP_001291581.1. NC_009567.1.

Genome annotation databases

EnsemblBacteriaiABQ99197; ABQ99197; CGSHiGG_00440.
GeneIDi5227881.
KEGGihiq:CGSHiGG_00440.
PATRICi20184315. VBIHaeInf102487_0089.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000672 Genomic DNA. Translation: ABQ99197.1 .
RefSeqi WP_011962031.1. NC_009567.1.
YP_001291581.1. NC_009567.1.

3D structure databases

ProteinModelPortali A5UEJ2.
SMRi A5UEJ2. Positions 119-730.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 374931.CGSHiGG_00440.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ99197 ; ABQ99197 ; CGSHiGG_00440 .
GeneIDi 5227881.
KEGGi hiq:CGSHiGG_00440.
PATRICi 20184315. VBIHaeInf102487_0089.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi AKLLFMG.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci HINF374931:GJA4-72-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains."
    Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D.
    Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PittGG.

Entry informationi

Entry nameiGLGB_HAEIG
AccessioniPrimary (citable) accession number: A5UEJ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 10, 2007
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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