Reviewed, UniProtKB/Swiss-Prot A5UE38 (GLPE_HAEIE)

Names and origin

Protein names

Recommended name:
    Thiosulfate sulfurtransferase glpE
    EC=2.8.1.1

Gene names

Name:	glpE
Ordered Locus Names:	CGSHiEE_08700

Organism

Haemophilus influenzae (strain PittEE) [Complete proteome] [HAMAP]

Taxonomic identifier

374930 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide By similarity.
Catalytic activity	Thiosulfate + cyanide = sulfite + thiocyanate. HAMAP MF_01009
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glpE family. Contains 1 rhodanese domain.

Ontologies

Keywords
Biological process	Glycerol metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	thiosulfate sulfurtransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	Thiosulfate sulfurtransferase glpE HAMAP MF_01009		PRO_1000062962
Regions
	Domain	15 – 103	89	Rhodanese
Sites
	Active site	63	1	Cysteine persulfide intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5UE38-1 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 33DC8DDB81271B57	FASTA	105	11,994
	10 20 30 40 50 60 MSFKEITPQQ AWEMMQQGAI LVDIRDNMRF AYSHPKGAFH LTNQSFLQFE ELADFDSPII 70 80 90 100 VSCYHGVSSR NVATFLVEQG YENVFSMIGG FDGWCRAELP IDTAY

References

[1]

"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains." Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D. Genome Biol. 8:RESEARCH103.1-RESEARCH103.18(2007) [PubMed: 17550610] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000671 Genomic DNA. Translation: ABQ99039.1.
RefSeq	YP_001291422.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5UE38.
Genome annotation databases
GeneID	5225579.
GenomeReviews	Gene locus CGSHiEE_08700 in contig CP000671_GR.
KEGG	hip:CGSHiEE_08700.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FSAWHEA.
Family and domain databases
HAMAP	MF_01009. [Tree]
InterPro	IPR001763. Rhodanese-like. [Graphical view]
Gene3D	G3DSA:3.40.250.10. Rhodanese-like. 1 hit.
Pfam	PF00581. Rhodanese. 1 hit. [Graphical view]
SMART	SM00450. RHOD. 1 hit. [Graphical view]
PROSITE	PS50206. RHODANESE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLPE_HAEIE

Accession

Primary (citable) accession number: A5UE38

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 10, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)