Reviewed, UniProtKB/Swiss-Prot A5UBF9 (GLND_HAEIE)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	CGSHiEE_03445

Organism

Haemophilus influenzae (strain PittEE) [Complete proteome] [HAMAP]

Taxonomic identifier

374930 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	863 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 863	863	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000022344

Sequences

	Sequence		Length	Mass (Da)
	A5UBF9-1 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: FBC5A42D0FFB0B92	FASTA	863	100,197
	10 20 30 40 50 60 MLFPLSLSSP LTPSAVKIER ENLKQFELEN FSRYSIFELV ENRSDFYDAL LIQLWQEMGL 70 80 90 100 110 120 SEQLGISLIA VGGYGRREMF PLSDLDFLIL VEQTPIPEIE EKITQFIQFL WDCGFEVGHS 130 140 150 160 170 180 VRTLQQCESE GKQDITIATN LLEARFLIGN RPHFDALNEL VKRADFWSKE GFFNAKVQEQ 190 200 210 220 230 240 IERYQRYHNT AYNLEPDIKY SPGGLRDLHL LYWVALHHSG AQTLEDILQS GFIYPQEYQQ 250 260 270 280 290 300 LQESRAFLFK VRFALHLILT RYDNRLLFDR QIKVSELLGF RGEGNQAVEK MMKCFFQALH 310 320 330 340 350 360 RISLISNLLI QHYRENVLSS NQATVIEQLD DDFQLINQCL CLRNSLVFQE KPARILDLFF 370 380 390 400 410 420 YLTQYEQANI HSDTLRQLQI SLEQLPQKLC EIPEAREKFL RLFNQPNSIK RAFMPMHQYG 430 440 450 460 470 480 VLTAYLPQWQ AIEGLMQFDL FHIYTVDEHT LRVMLKLESF LSQESAQEHP IAHRIFSQLS 490 500 510 520 530 540 DRTLLYIAAL FHDIAKGRGG DHAELGAKDV ANFARLHGLD RREIDTLAWL VQSHLLMSIT 550 560 570 580 590 600 AQRRDIHDPE VVMNFAEAVQ NQVRLDYLTC LTVADICATN GNLWNSWKRS LFASLYEFTE 610 620 630 640 650 660 QQFAQGMKEL LDYSEKSAEN RKLAQQILTQ DYSDIMPISI DQLWERCPED YFVRNTPKQI 670 680 690 700 710 720 AWHTSLLVDL VEALLVKISN RFSLGGTEVF IYCQDQPHLF NKVVSTIGAK KFSIHDAQII 730 740 750 760 770 780 TTQDGYVFDS FIITELNGEL VEFDRRRELE QALTLALQSE KLSALSITPN RQLQHFTVQT 790 800 810 820 830 840 DVRFLHENKK EHTEMELVAL DKAGLLAQVS QIFSELNLNL LNAKITTVGE KAEDFFILTN 850 860 QFGQALDSQQ REILRNVLYR NIG

References

[1]

"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains." Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D. Genome Biol. 8:RESEARCH103.1-RESEARCH103.18(2007) [PubMed: 17550610] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000671 Genomic DNA. Translation: ABQ98110.1.
RefSeq	YP_001290493.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5UBF9.
Genome annotation databases
GeneID	5225241.
GenomeReviews	Gene locus CGSHiEE_03445 in contig CP000671_GR.
KEGG	hip:CGSHiEE_03445.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MQHDLFH.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_HAEIE

Accession

Primary (citable) accession number: A5UBF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 10, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)