A5UB16 (DCD_HAEIE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CGSHiEE_02630

Organism

Haemophilus influenzae (strain PittEE) [Complete proteome] [HAMAP]

Taxonomic identifier

374930 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009733

Sequences

	Sequence		Length	Mass (Da)
	A5UB16 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 39EC2C26683748CE	FASTA	195	21,578
	10 20 30 40 50 60 MRLCDTDIER YLDDGIISLT PRPNNDKING ATIDVRLGNS FRVFREHSAP FIDLSGPKEE 70 80 90 100 110 120 VSAQLESVMS DEILIPEGEA FFLHPGTLAL ATTLESVKLP ANIIGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WEGKIVLEFY NSGKLPLALR PNMVIGALSF EVLSGEAKRP YSSRKDAKYK 190 NQQSAVASRI DEDKE

References

[1]

"Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains." Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C., Ehrlich G.D. Genome Biol. 8:R103.1-R103.18(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PittEE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000671 Genomic DNA. Translation: ABQ97967.1.
RefSeq	YP_001290350.1. NC_009566.1.
3D structure databases
ProteinModelPortal	A5UB16.
SMR	A5UB16. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	374930.CGSHiEE_02630.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABQ97967; ABQ97967; CGSHiEE_02630.
GeneID	5224979.
KEGG	hip:CGSHiEE_02630.
PATRIC	20277118. VBIHaeInf81350_0533.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	HINF374930:GJDD-494-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR010550. dCTP_deam_bac. [Graphical view]
Pfam	PF06559. DCD. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_HAEIE

Accession

Primary (citable) accession number: A5UB16

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 10, 2007
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program