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Protein
Submitted name:

Uncharacterized protein

Gene

MRA_3947

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-4068-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:MRA_3947Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi419947.MtubH3_010100016037.

Structurei

3D structure databases

ProteinModelPortaliA5U9N6.
SMRiA5U9N6. Positions 64-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini62 – 198137Nudix hydrolaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the Nudix hydrolase family.UniRule annotation
Contains nudix hydrolase domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4108WNV. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000261976.
OMAiMHETSAG.
OrthoDBiEOG6SR962.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5U9N6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDGEQAKSR RRRGRRRGRR AAATAENHMD AQPAGDATPT PATAKRSRSR
60 70 80 90 100
SPRRGSTRMR TVHETSAGGL VIDGIDGPRD AQVAALIGRV DRRGRLLWSL
110 120 130 140 150
PKGHIELGET AEQTAIREVA EETGIRGSVL AALGRIDYWF VTDGRRVHKT
160 170 180 190 200
VHHYLMRFLG GELSDEDLEV AEVAWVPIRE LPSRLAYADE RRLAEVADEL
210 220 230 240
IDKLQSDGPA ALPPLPPSSP RRRPQTHSRA RHADDSAPGQ HNGPGPGP
Length:248
Mass (Da):27,171
Last modified:July 10, 2007 - v1
Checksum:i270A5193861EADD3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ75736.1.
RefSeqiWP_003400124.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ75736; ABQ75736; MRA_3947.
KEGGimra:MRA_3947.
PATRICi18148455. VBIMycTub106795_4405.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ75736.1.
RefSeqiWP_003400124.1. NC_009525.1.

3D structure databases

ProteinModelPortaliA5U9N6.
SMRiA5U9N6. Positions 64-205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MtubH3_010100016037.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ75736; ABQ75736; MRA_3947.
KEGGimra:MRA_3947.
PATRICi18148455. VBIMycTub106795_4405.

Phylogenomic databases

eggNOGiENOG4108WNV. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000261976.
OMAiMHETSAG.
OrthoDBiEOG6SR962.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-4068-MONOMER.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv."
    Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L., Wang H., Wang S., Zhao G., Zhang Y.
    PLoS ONE 3:E2375-E2375(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25177 / H37RaImported.

Entry informationi

Entry nameiA5U9N6_MYCTA
AccessioniPrimary (citable) accession number: A5U9N6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 16, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.