Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase

Gene

sodA

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-4007-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodAImported
Ordered Locus Names:MRA_3886Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001988 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi419947.MRA_3886.

Structurei

3D structure databases

ProteinModelPortaliA5U9H5.
SMRiA5U9H5. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0605.
HOGENOMiHOG000013583.
KOiK04564.
OMAiVNWDDVE.
OrthoDBiEOG63NMNT.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5U9H5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYTLPDLD WDYGALEPHI SGQINELHHS KHHATYVKGA NDAVAKLEEA
60 70 80 90 100
RAKEDHSAIL LNEKNLAFNL AGHVNHTIWW KNLSPNGGDK PTGELAAAIA
110 120 130 140 150
DAFGSFDKFR AQFHAAATTV QGSGWAALGW DTLGNKLLIF QVYDHQTNFP
160 170 180 190 200
LGIVPLLLLD MWEHAFYLQY KNVKVDFAKA FWNVVNWADV QSRYAAATSQ

TKGLIFG
Length:207
Mass (Da):23,034
Last modified:July 10, 2007 - v1
Checksum:iDEE8F5921DABE54A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ75675.1.
RefSeqiYP_001285237.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ75675; ABQ75675; MRA_3886.
KEGGimra:MRA_3886.
PATRICi18148313. VBIMycTub106795_4334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ75675.1.
RefSeqiYP_001285237.1. NC_009525.1.

3D structure databases

ProteinModelPortaliA5U9H5.
SMRiA5U9H5. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MRA_3886.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ75675; ABQ75675; MRA_3886.
KEGGimra:MRA_3886.
PATRICi18148313. VBIMycTub106795_4334.

Phylogenomic databases

eggNOGiCOG0605.
HOGENOMiHOG000013583.
KOiK04564.
OMAiVNWDDVE.
OrthoDBiEOG63NMNT.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-4007-MONOMER.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv."
    Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L., Wang H., Wang S., Zhao G., Zhang Y.
    PLoS ONE 3:E2375-E2375(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25177 / H37RaImported.

Entry informationi

Entry nameiA5U9H5_MYCTA
AccessioniPrimary (citable) accession number: A5U9H5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 1, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.