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A5U8D8

- IF1_MYCTA

UniProt

A5U8D8 - IF1_MYCTA

Protein

Translation initiation factor IF-1

Gene

infA

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciMTUB419947:GJ8N-3613-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-1UniRule annotation
    Gene namesi
    Name:infAUniRule annotation
    Ordered Locus Names:MRA_3503
    OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
    Taxonomic identifieri419947 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000001988: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7373Translation initiation factor IF-1PRO_0000338865Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi419947.MRA_3503.

    Structurei

    3D structure databases

    ProteinModelPortaliA5U8D8.
    SMRiA5U8D8. Positions 6-73.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 7373S1-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IF-1 family.UniRule annotation
    Contains 1 S1-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0361.
    HOGENOMiHOG000221323.
    KOiK02518.
    OMAiKGRIIWR.
    OrthoDBiEOG6384SC.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00075. IF_1.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view]
    PfamiPF01176. eIF-1a. 1 hit.
    [Graphical view]
    SMARTiSM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00008. infA. 1 hit.
    PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5U8D8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKKDGAIEV EGRVVEPLPN AMFRIELENG HKVLAHISGK MRQHYIRILP   50
    EDRVVVELSP YDLSRGRIVY RYK 73
    Length:73
    Mass (Da):8,489
    Last modified:July 10, 2007 - v1
    Checksum:i70CEB2A79E874448
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000611 Genomic DNA. Translation: ABQ75288.1.
    RefSeqiYP_001284850.1. NC_009525.1.

    Genome annotation databases

    EnsemblBacteriaiABQ75288; ABQ75288; MRA_3503.
    GeneIDi5214332.
    KEGGimra:MRA_3503.
    PATRICi18147448. VBIMycTub106795_3909.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000611 Genomic DNA. Translation: ABQ75288.1 .
    RefSeqi YP_001284850.1. NC_009525.1.

    3D structure databases

    ProteinModelPortali A5U8D8.
    SMRi A5U8D8. Positions 6-73.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 419947.MRA_3503.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ75288 ; ABQ75288 ; MRA_3503 .
    GeneIDi 5214332.
    KEGGi mra:MRA_3503.
    PATRICi 18147448. VBIMycTub106795_3909.

    Phylogenomic databases

    eggNOGi COG0361.
    HOGENOMi HOG000221323.
    KOi K02518.
    OMAi KGRIIWR.
    OrthoDBi EOG6384SC.

    Enzyme and pathway databases

    BioCyci MTUB419947:GJ8N-3613-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00075. IF_1.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view ]
    Pfami PF01176. eIF-1a. 1 hit.
    [Graphical view ]
    SMARTi SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00008. infA. 1 hit.
    PROSITEi PS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv."
      Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25177 / H37Ra.

    Entry informationi

    Entry nameiIF1_MYCTA
    AccessioniPrimary (citable) accession number: A5U8D8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 10, 2008
    Last sequence update: July 10, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3