A5U8D6 (RS13_MYCTA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S13

Gene names

Name:	rpsM
Ordered Locus Names:	MRA_3501

Organism

Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]

Taxonomic identifier

419947 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	124 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites By similarity. HAMAP MF_01315_B
Subunit structure	Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein S13P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 124	124	30S ribosomal protein S13 HAMAP MF_01315_B		PRO_0000306652

Sequences

	Sequence		Length	Mass (Da)
	A5U8D6 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 93B44CB17A4503B1	FASTA	124	14,351
	10 20 30 40 50 60 MARLVGVDLP RDKRMEVALT YIFGIGRTRS NEILAATGID RDLRTRDLTE EQLIHLRDYI 70 80 90 100 110 120 EANLKVEGDL RREVQADIRR KIEIGCYQGL RHRRGMPVRG QRTKTNARTR KGPKRTIAGK KKAR

References

[1]

"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv." Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25177 / H37Ra.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000611 Genomic DNA. Translation: ABQ75286.1.
RefSeq	YP_001284848.1. NC_009525.1.
3D structure databases
ProteinModelPortal	A5U8D6.
SMR	A5U8D6. Positions 2-123.
ModBase	Search...
Protein-protein interaction databases
STRING	A5U8D6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000068075; EBMYCP00000066185; EBMYCG00000068070.
GeneID	5214330.
GenomeReviews	Gene locus MRA_3501 in contig CP000611_GR.
KEGG	mra:MRA_3501.
PATRIC	18147444. VBIMycTub106795_3907.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0099.
GeneTree	EBGT00050000015674.
HOGENOM	HBG737405.
OMA	YRGRRHR.
ProtClustDB	PRK05179.
Enzyme and pathway databases
BioCyc	MTUB419947:MRA_3501-MONOMER.
Family and domain databases
HAMAP	MF_01315_B. Ribosomal_S13_B. [Tree]
InterPro	IPR001892. Ribosomal_S13. IPR010979. Ribosomal_S13-like_H2TH. IPR019980. Ribosomal_S13_bac-type. IPR018269. Ribosomal_S13_CS. [Graphical view]
KO	K02952.
PANTHER	PTHR10871. PTHR10871. 1 hit.
Pfam	PF00416. Ribosomal_S13. 1 hit. [Graphical view]
PIRSF	PIRSF002134. Ribosomal_S13. 1 hit.
SUPFAM	SSF46946. Ribosomal_H2TH. 1 hit.
TIGRFAMs	TIGR03631. Bact_S13. 1 hit.
PROSITE	PS00646. RIBOSOMAL_S13_1. 1 hit. PS50159. RIBOSOMAL_S13_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS13_MYCTA

Accession

Primary (citable) accession number: A5U8D6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program