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Protein

Glutamate decarboxylase

Gene

gadB

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
Ordered Locus Names:MRA_3473Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei277N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi419947.MtubH3_010100011825

Structurei

3D structure databases

ProteinModelPortaliA5U8A8
SMRiA5U8A8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

A5U8A8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM
60 70 80 90 100
LDGSSRLNLA TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV
110 120 130 140 150
SMVADLFHAE GLRDHDPTSA TGVSTIGSSE AVMLGGLALK WRWRQRVGSW
160 170 180 190 200
KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY LPMERGRYVI TPEQVLAAVD
210 220 230 240 250
ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP VHVDAASGGF
260 270 280 290 300
VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL
310 320 330 340 350
VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT
360 370 380 390 400
ARWLGDQLRE VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW
410 420 430 440 450
QVPAYTMPDN ATDVAVLRIV VREGLSADLA RALHDDAVTA LAALDKVKPG
460
GHFDAQHFAH
Length:460
Mass (Da):50,780
Last modified:July 10, 2007 - v1
Checksum:iB5DA3156D4C7CB4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA Translation: ABQ75258.1
RefSeqiWP_003418277.1, NZ_CP016972.1

Genome annotation databases

EnsemblBacteriaiABQ75258; ABQ75258; MRA_3473
KEGGimra:MRA_3473

Similar proteinsi

Entry informationi

Entry nameiA5U8A8_MYCTA
AccessioniPrimary (citable) accession number: A5U8A8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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