A5U7B5 (SSRP_MYCTA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	MRA_3132

Organism

Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]

Taxonomic identifier

419947 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP MF_00023
Subcellular location	Cytoplasm Potential HAMAP MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	SsrA-binding protein HAMAP MF_00023		PRO_1000002087

Sequences

	Sequence		Length	Mass (Da)
	A5U7B5 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 949F6327A03ACCD3	FASTA	160	18,230
	10 20 30 40 50 60 MSKSSRGGRQ IVASNRKARH NYSIIEVFEA GVALQGTEVK SLREGQASLA DSFATIDDGE 70 80 90 100 110 120 VWLRNAHIPE YRHGSWTNHE PRRNRKLLLH RRQIDTLVGK IREGNFALVP LSLYFAEGKV 130 140 150 160 KVELALARGK QARDKRQDMA RRDAQREVLR ELGRRAKGMT

References

[1]

"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv." Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25177 / H37Ra.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000611 Genomic DNA. Translation: ABQ74915.1.
RefSeq	YP_001284477.1. NC_009525.1.
3D structure databases
ProteinModelPortal	A5U7B5.
SMR	A5U7B5. Positions 11-130.
ModBase	Search...
Protein-protein interaction databases
STRING	A5U7B5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000068288; EBMYCP00000066398; EBMYCG00000068283.
GeneID	5212763.
GenomeReviews	Gene locus MRA_3132 in contig CP000611_GR.
KEGG	mra:MRA_3132.
PATRIC	18146635. VBIMycTub106795_3504.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0691.
GeneTree	EBGT00050000017126.
HOGENOM	HBG293422.
OMA	EKYEAGI.
ProtClustDB	PRK05422.
Enzyme and pathway databases
BioCyc	MTUB419947:MRA_3132-MONOMER.
Family and domain databases
HAMAP	MF_00023. SmpB. [Tree]
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Gene3D	G3DSA:2.40.280.10. SmpB. 1 hit.
KO	K03664.
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. SmpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_MYCTA

Accession

Primary (citable) accession number: A5U7B5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program