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Protein
Submitted name:

Penicillin-binding membrane protein PbpB

Gene

pbpB

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-2247-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Penicillin-binding membrane protein PbpBImported
Gene namesi
Name:pbpBImported
Ordered Locus Names:MRA_2178Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei93 – 11119HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi419947.MRA_2178.

Structurei

3D structure databases

ProteinModelPortaliA5U4J0.
SMRiA5U4J0. Positions 133-667.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini131 – 294164PBP_dimerInterPro annotationAdd
BLAST
Domaini339 – 654316TranspeptidaseInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105CJN. Bacteria.
COG0768. LUCA.
HOGENOMiHOG000049553.
KOiK03587.
OMAiKRRFIYL.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR005311. PBP_dimer.
IPR001460. PCN-bd_Tpept.
[Graphical view]
PfamiPF03717. PBP_dimer. 1 hit.
PF00905. Transpeptidase. 1 hit.
[Graphical view]
SUPFAMiSSF56519. SSF56519. 1 hit.
SSF56601. SSF56601. 1 hit.

Sequencei

Sequence statusi: Complete.

A5U4J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRAAPRRAS QSQSTRPARG LRRPPGAQEV GQRKRPGKTQ KARQAQEATK
60 70 80 90 100
SRPATRSDVA PAGRSTRARR TRQVVDVGTR GASFVFRHRT GNAVILVLML
110 120 130 140 150
VAATQLFFLQ VSHAAGLRAQ AAGQLKVTDV QPAARGSIVD RNNDRLAFTI
160 170 180 190 200
EARALTFQPK RIRRQLEEAR KKTSAAPDPQ QRLRDIAQEV AGKLNNKPDA
210 220 230 240 250
AAVLKKLQSD ETFVYLARAV DPAVASAICA KYPEVGAERQ DLRQYPGGSL
260 270 280 290 300
AANVVGGIDW DGHGLLGLED SLDAVLAGTD GSVTYDRGSD GVVIPGSYRN
310 320 330 340 350
RHKAVHGSTV VLTLDNDIQF YVQQQVQQAK NLSGAHNVSA VVLDAKTGEV
360 370 380 390 400
LAMANDNTFD PSQDIGRQGD KQLGNPAVSS PFEPGSVNKI VAASAVIEHG
410 420 430 440 450
LSSPDEVLQV PGSIQMGGVT VHDAWEHGVM PYTTTGVFGK SSNVGTLMLS
460 470 480 490 500
QRVGPERYYD MLRKFGLGQR TGVGLPGESA GLVPPIDQWS GSTFANLPIG
510 520 530 540 550
QGLSMTLLQM TGMYQAIAND GVRVPPRIIK ATVAPDGSRT EEPRPDDIRV
560 570 580 590 600
VSAQTAQTVR QMLRAVVQRD PMGYQQGTGP TAGVPGYQMA GKTGTAQQIN
610 620 630 640 650
PGCGCYFDDV YWITFAGIAT ADNPRYVIGI MLDNPARNSD GAPGHSAAPL
660 670
FHNIAGWLMQ RENVPLSPDP GPPLVLQAT
Length:679
Mass (Da):72,537
Last modified:July 10, 2007 - v1
Checksum:i3FE57B17A4D265C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ73940.1.
RefSeqiWP_003411214.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ73940; ABQ73940; MRA_2178.
KEGGimra:MRA_2178.
PATRICi18144483. VBIMycTub106795_2443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ73940.1.
RefSeqiWP_003411214.1. NC_009525.1.

3D structure databases

ProteinModelPortaliA5U4J0.
SMRiA5U4J0. Positions 133-667.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MRA_2178.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ73940; ABQ73940; MRA_2178.
KEGGimra:MRA_2178.
PATRICi18144483. VBIMycTub106795_2443.

Phylogenomic databases

eggNOGiENOG4105CJN. Bacteria.
COG0768. LUCA.
HOGENOMiHOG000049553.
KOiK03587.
OMAiKRRFIYL.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-2247-MONOMER.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR005311. PBP_dimer.
IPR001460. PCN-bd_Tpept.
[Graphical view]
PfamiPF03717. PBP_dimer. 1 hit.
PF00905. Transpeptidase. 1 hit.
[Graphical view]
SUPFAMiSSF56519. SSF56519. 1 hit.
SSF56601. SSF56601. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA5U4J0_MYCTA
AccessioniPrimary (citable) accession number: A5U4J0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.