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Protein
Submitted name:

ABC transporter ATP-binding protein

Gene

MRA_1831

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi460 – 467ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-1892-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ABC transporter ATP-binding proteinImported
Gene namesi
Ordered Locus Names:MRA_1831Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 44HelicalSequence analysisAdd BLAST25
Transmembranei65 – 86HelicalSequence analysisAdd BLAST22
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Transmembranei214 – 235HelicalSequence analysisAdd BLAST22
Transmembranei255 – 277HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA5U3I6.

Interactioni

Protein-protein interaction databases

STRINGi419947.MRA_1831.

Structurei

3D structure databases

ProteinModelPortaliA5U3I6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 393ABC transmembrane type-1InterPro annotationAdd BLAST326
Domaini427 – 639ABC transporterInterPro annotationAdd BLAST213

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105CQ0. Bacteria.
COG4178. LUCA.
HOGENOMiHOG000255118.
KOiK02471.
OMAiTIIHMNR.

Family and domain databases

Gene3Di1.20.1560.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 3 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A5U3I6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPKLFKPSI DWSRAFPDSV YWVGKAWTIS AICVLAILVL LRYLTPWGRQ
60 70 80 90 100
FWRITRAYFV GPNSVRVWLM LGVLLLSVVL AVRLNVLFSY QGNDMYTALQ
110 120 130 140 150
KAFEGIASGD GTVKRSGVRG FWMSIGVFSV MAVLHVTRVM ADIYLTQRFI
160 170 180 190 200
IAWRVWLTHH LTQDWLDGRA YYRDLFIDET IDNPDQRIQQ DVDIFTAGAG
210 220 230 240 250
GTPNAPSNGT ASTLLFGAVQ SIISVISFTA ILWNLSGTLN IFGVSIPRAM
260 270 280 290 300
FWTVLVYVFV ATVISFIIGR PLIWLSFRNE KLNAAFRYAL VRLRDAAEAV
310 320 330 340 350
GFYRGERVEG TQLQRRFTPV IDNYRRYVRR SIAFNGWNLS VSQTIVPLPW
360 370 380 390 400
VIQAPRLFAG QIDFGDVGQT ATSFGNIHDS LSFFRNNYDA FASFRAAIIR
410 420 430 440 450
LHGLVDANEK GRALPAVLTR PSDDESVELN DIEVRTPAGD RLIDPLDVRL
460 470 480 490 500
DRGGSLVITG RSGAGKTTLL RSLAELWPYA SGTLHRPGGE NETMFLSQLP
510 520 530 540 550
YVPLGTLRDV VCYPNSAAAI PDATLRDTLT KVALAPLCDR LDEERDWAKV
560 570 580 590 600
LSPGEQQRVA FARILLTKPK AVFLDESTSA LDTGLEFALY QLLRSELPDC
610 620 630
IVISVSHRPA LERLHENQLE LLGGGQWRLA PVEAAPAEV
Length:639
Mass (Da):71,317
Last modified:July 10, 2007 - v1
Checksum:iDE85BBEEF42759A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ73586.1.
RefSeqiWP_003900416.1. NZ_CP016972.1.

Genome annotation databases

EnsemblBacteriaiABQ73586; ABQ73586; MRA_1831.
KEGGimra:MRA_1831.

Similar proteinsi

Entry informationi

Entry nameiA5U3I6_MYCTA
AccessioniPrimary (citable) accession number: A5U3I6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 25, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported