A5U2F0 (A5U2F0_MYCTA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	zwf2 EMBL ABQ73200.1
Ordered Locus Names:	MRA_1456

Organism

Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]

Taxonomic identifier

419947 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	514 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5U2F0 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 22A9CCEDC9AB062F	FASTA	514	57,343
	10 20 30 40 50 60 MKPAHAAASW RNPLRDKRDK RLPRIAGPCG MVIFGVTGDL ARKKVMPAVY DLANRGLLPP 70 80 90 100 110 120 TFSLVGFARR DWSTQDFGQV VYNAVQEHCR TPFRQQNWDR LAEGFRFVPG TFDDDDAFAQ 130 140 150 160 170 180 LAETLEKLDA ERGTGGNHAF YLAIPPKSFP VVCEQLHKSG LARPQGDRWS RVVIEKPFGH 190 200 210 220 230 240 DLASARELNK AVNAVFPEEA VFRIDHYLGK ETVQNILALR FANQLFDPIW NAHYVDHVQI 250 260 270 280 290 300 TMAEDIGLGG RAGYYDGIGA ARDVIQNHLM QLLALTAMEE PVSFHPAALQ AEKIKVLSAT 310 320 330 340 350 360 RLAEPLDQTT SRGQYAAGWQ GGEKVVGLLD EEGFAEDSTT ETFAAITLEV DTRRWAGVPF 370 380 390 400 410 420 YLRTGKRLGR RVTEIALVFR RAPHLPFDAT MTDELGTNAM VIRVQPDEGV TLRFGSKVPG 430 440 450 460 470 480 TAMEVRDVNM DFSYGSAFAE DSPEAYERLI LDVLLGEPSL FPVNAEVELA WEILDPALEH 490 500 510 WAAHGTPDAY EAGTWGPESS LEMLRRTGRE WRRP

References

[1]

"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv." Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000611 Genomic DNA. Translation: ABQ73200.1.
RefSeq	YP_001282762.1. NC_009525.1.
3D structure databases
ProteinModelPortal	A5U2F0.
ModBase	Search...
Protein-protein interaction databases
STRING	A5U2F0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000065130; EBMYCP00000063240; EBMYCG00000065125.
GeneID	5215348.
GenomeReviews	Gene locus MRA_1456 in contig CP000611_GR.
KEGG	mra:MRA_1456.
PATRIC	18142841. VBIMycTub106795_1622.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
GeneTree	EBGT00050000015853.
HOGENOM	HBG322449.
OMA	FANQMFE.
ProtClustDB	PRK05722.
Family and domain databases
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00036.
PANTHER	PTHR23429. G6PDH. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. Zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5U2F0_MYCTA

Accession

Primary (citable) accession number: A5U2F0

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)