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A5U146 (A5U146_MYCTA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:MRA_1012
OrganismMycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]
Taxonomic identifier419947 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
   Biological processrRNA processing HAMAP MF_01877
   Cellular componentCytoplasm HAMAP MF_01877
   LigandS-adenosyl-L-methionine HAMAP MF_01877
   Molecular functionMethyltransferase HAMAP MF_01877
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processenzyme-directed rRNA 2'-O-methylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (cytosine-2'-O-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A5U146 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 2F799A8057F64634

FASTA28529,665
        10         20         30         40         50         60 
MSSGRLLLGA TPLGQPSDAS PRLAAALATA DVVAAEDTRR VRKLAKALDI RIGGRVVSLF 

        70         80         90        100        110        120 
DRVEALRVTA LLDAINNGAT VLVVSDAGTP VISDPGYRLV AACIDAGVSV TCLPGPSAVT 

       130        140        150        160        170        180 
TALVMSGLPA EKFCFEGFAP RKGAARRAWL AELAEERRTC VFFESPRRLA ACLNDAVEQL 

       190        200        210        220        230        240 
GGARPAAICR ELTKVHEEVV RGSLDELAIW AAGGVLGEIT VVVAGAAPHA ELSSLIAQVE 

       250        260        270        280 
EFVAAGIRVK DACSEVAAAH PGVRTRQLYD AVLQSRRETG GPAQP

« Hide

References

[1]"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv."
Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000611 Genomic DNA. Translation: ABQ72746.1.
RefSeqYP_001282308.1. NC_009525.1.

3D structure databases

ProteinModelPortalA5U146.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5U146.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000066361; EBMYCP00000064471; EBMYCG00000066356.
GeneID5215426.
GenomeReviewsGene locus MRA_1012 in contig CP000611_GR.
KEGGmra:MRA_1012.
PATRIC18141820. VBIMycTub106795_1119.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0313.
GeneTreeEBGT00050000017256.
HOGENOMHBG529058.
OMAIASDRFC.
ProtClustDBCLSK790887.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5U146_MYCTA
AccessionPrimary (citable) accession number: A5U146
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info