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A5TZD4 (A5TZD4_MYCTA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase PIRNR PIRNR006107
EC=2.3.1.8 PIRNR PIRNR006107
Alternative name(s):
Phosphotransacetylase PIRNR PIRNR006107
Gene names
Name:pta EMBL ABQ72134.1
Ordered Locus Names:MRA_0414
OrganismMycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]
Taxonomic identifier419947 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length690 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity. PIRNR PIRNR006107

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate. PIRNR PIRNR006107

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2. PIRNR PIRNR006107

Subcellular location

Cytoplasm By similarity PIRNR PIRNR006107.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity. PIRNR PIRNR006107

Sequence similarities

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. PIRNR PIRNR006107

In the N-terminal section; belongs to the CobB/CobQ family. PIRNR PIRNR006107

Ontologies

Keywords
   Cellular componentCytoplasm PIRNR PIRNR006107
   Molecular functionAcyltransferase PIRNR PIRNR006107
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A5TZD4 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: C01C412AF2810CCE

FASTA69072,949
        10         20         30         40         50         60 
MADSSAIYLA APESQTGKST IALGLLHRLT AMVAKVGVFR PITRLSAERD YILELLLAHT 

        70         80         90        100        110        120 
SAGLPYERCV GVTYQQLHAD RDDAIAEIVD SYHAMADECD AVVVVGSDYT DVTSPTELSV 

       130        140        150        160        170        180 
NGRIAVNLGA PVLLTVRAKD RTPDQVASVV EVCLAELDTQ RAHTAAVVAN RCELSAIPAV 

       190        200        210        220        230        240 
TDALRRFTPP SYVVPEEPLL SAPTVAELTQ AVNGAVVSGD VALREREVMG VLAAGMTADH 

       250        260        270        280        290        300 
VLERLTDGMA VITPGDRSDV VLAVASAHAA EGFPSLSCIV LNGGFQLHPA IAALVSGLRL 

       310        320        330        340        350        360 
RLPVIATALG TYDTASAAAS ARGLVTATSQ RKIDTALELM DRHVDVAGLL AQLTIPIPTV 

       370        380        390        400        410        420 
TTPQMFTYRL LQQARSDLMR IVLPEGDDDR ILKSAGRLLQ RGIVDLTILG DEAKVRLRAA 

       430        440        450        460        470        480 
ELGVDLDGAT VIEPCASELH DQFADQYAQL RKAKGITVEH AREIMNDATY FGTMLVHNCH 

       490        500        510        520        530        540 
ADGMVSGAAH TTAHTVRPAL EIIKTVPGIS TVSSIFLMCL PDRVLAYGDC AIIPNPTVEQ 

       550        560        570        580        590        600 
LADIAICSAR TAAQFGIEPR VAMLSYSTGD SGKGADVDKV RAATELVRAR EPQLPVEGPI 

       610        620        630        640        650        660 
QYDAAVEPSV AATKLRDSPV AGRATVLIFP DLNTGNNTYK AVQRSAGAIA IGPVLQGLRK 

       670        680        690 
PVNDLSRGAL VDDIVNTVAI TAIQAQGVHE

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References

[1]"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv."
Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000611 Genomic DNA. Translation: ABQ72134.1.
RefSeqYP_001281696.1. NC_009525.1.

3D structure databases

ProteinModelPortalA5TZD4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5TZD4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000066591; EBMYCP00000064701; EBMYCG00000066586.
GeneID5212998.
GenomeReviewsGene locus MRA_0414 in contig CP000611_GR.
KEGGmra:MRA_0414.
PATRIC18140454. VBIMycTub106795_0448.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0857.
GeneTreeEBGT00050000017507.
HOGENOMHBG576804.
OMAVTPLMFE.
ProtClustDBPRK05632.

Family and domain databases

InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
KOK13788.
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMsTIGR00651. Pta. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5TZD4_MYCTA
AccessionPrimary (citable) accession number: A5TZD4
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info