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Protein
Submitted name:

3-ketoacyl-(Acyl-carrier-protein) reductase

Gene

fabG-1

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-253-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
3-ketoacyl-(Acyl-carrier-protein) reductaseImported
Gene namesi
Name:fabG-1Imported
Ordered Locus Names:MRA_0251Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi419947.MtubH3_010100013397.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LLSX-ray2.40A/B1-454[»]
ProteinModelPortaliA5TYW8.
SMRiA5TYW8. Positions 20-454.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA5TYW8.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105RN6. Bacteria.
COG1028. LUCA.
HOGENOMiHOG000245099.
KOiK00059.
OMAiLYDFFHP.
OrthoDBiEOG6N3CR8.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5TYW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKRSSDLF SQVVNSGPGS FLARQLGVPQ PETLRRYRAG EPPLTGSLLI
60 70 80 90 100
GGAGRVVEPL RAALEKDYDL VGNNLGGRWA DSFGGLVFDA TGITEPAGLK
110 120 130 140 150
GLHEFFTPVL RNLGRCGRVV VVGGTPEAAA STNERIAQRA LEGFTRSLGK
160 170 180 190 200
ELRRGATTAL VYLSPDAKPA ATGLESTMRF LLSAKSAYVD GQVFSVGADD
210 220 230 240 250
STPPADWEKP LDGKVAIVTG AARGIGATIA EVFARDGAHV VAIDVESAAE
260 270 280 290 300
NLAETASKVG GTALWLDVTA DDAVDKISEH LRDHHGGKAD ILVNNAGITR
310 320 330 340 350
DKLLANMDDA RWDAVLAVNL LAPLRLTEGL VGNGSIGEGG RVIGLSSIAG
360 370 380 390 400
IAGNRGQTNY ATTKAGMIGI TQALAPGLAA KGITINAVAP GFIETQMTAA
410 420 430 440 450
IPLATREVGR RLNSLLQGGQ PVDVAEAIAY FASPASNAVT GNVIRVCGQA

MIGA
Length:454
Mass (Da):46,830
Last modified:July 10, 2007 - v1
Checksum:iC5B89B6FEA38BD91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71968.1.
RefSeqiWP_003899869.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ71968; ABQ71968; MRA_0251.
KEGGimra:MRA_0251.
PATRICi18140103. VBIMycTub106795_0273.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71968.1.
RefSeqiWP_003899869.1. NC_009525.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LLSX-ray2.40A/B1-454[»]
ProteinModelPortaliA5TYW8.
SMRiA5TYW8. Positions 20-454.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MtubH3_010100013397.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ71968; ABQ71968; MRA_0251.
KEGGimra:MRA_0251.
PATRICi18140103. VBIMycTub106795_0273.

Phylogenomic databases

eggNOGiENOG4105RN6. Bacteria.
COG1028. LUCA.
HOGENOMiHOG000245099.
KOiK00059.
OMAiLYDFFHP.
OrthoDBiEOG6N3CR8.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-253-MONOMER.

Miscellaneous databases

EvolutionaryTraceiA5TYW8.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv."
    Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L., Wang H., Wang S., Zhao G., Zhang Y.
    PLoS ONE 3:E2375-E2375(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25177 / H37RaImported.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS).

Entry informationi

Entry nameiA5TYW8_MYCTA
AccessioniPrimary (citable) accession number: A5TYW8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: May 11, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.