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Protein
Submitted name:

Cation-transporting P-type ATPase B

Gene

ctpB

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi26PROSITE-ProRule annotation1
Metal bindingi29PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cation-transporting P-type ATPase BImported
Gene namesi
Name:ctpBImported
Ordered Locus Names:MRA_0108Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei105 – 126HelicalUniRule annotationAdd BLAST22
Transmembranei132 – 150HelicalUniRule annotationAdd BLAST19
Transmembranei170 – 188HelicalUniRule annotationAdd BLAST19
Transmembranei208 – 226HelicalUniRule annotationAdd BLAST19
Transmembranei361 – 383HelicalUniRule annotationAdd BLAST23
Transmembranei389 – 410HelicalUniRule annotationAdd BLAST22
Transmembranei704 – 720HelicalUniRule annotationAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA5TYH7

Interactioni

Protein-protein interaction databases

STRINGi419947.MtubH3_010100009599

Structurei

3D structure databases

ProteinModelPortaliA5TYH7
SMRiA5TYH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 79HMAInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG2217 LUCA
HOGENOMiHOG000250397
KOiK12949
OMAiKASIYHP

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR000579 Cation-trans_P-type_ATPase_A/B
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
PRINTSiPR00940 CATPATPASEA
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit

Sequencei

Sequence statusi: Complete.

A5TYH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPVVGDAD LQSVRRIRLD VLGMSCAACA SRVETKLNKI PGVRASVNFA
60 70 80 90 100
TRVATIDAVG MAADELCGVV EKAGYHAAPH TETTVLDKRT KDPDGAHARR
110 120 130 140 150
LLRRLLVAAV LFVPLADLST LFAIVPSARV PGWGYILTAL AAPVVTWAAW
160 170 180 190 200
PFHSVALRNA RHRTTSMETL ISVGIVAATA WSLSSVFGDQ PPREGSGIWR
210 220 230 240 250
AILNSDSIYL EVAAGVTVFV LAGRYFEARA KSKAGSALRA LAELGAKNVA
260 270 280 290 300
VLLPDGAELV IPASELKKRQ RFVTRPGETI AADGVVVDGS AAIDMSAMTG
310 320 330 340 350
EAKPVRAYPA ASVVGGTVVM DGRLVIEATA VGADTQFAAM VRLVEQAQTQ
360 370 380 390 400
KARAQRLADH IAGVFVPVVF VIAGLAGAAW LVSGAGADRA FSVTLGVLVI
410 420 430 440 450
ACPCALGLAT PTAMMVASGR GAQLGIFIKG YRALETIRSI DTVVFDKTGT
460 470 480 490 500
LTVGQLAVST VTMAGSGTSE RDREEVLGLA AAVESASEHA MAAAIVAASP
510 520 530 540 550
DPGPVNGFVA VAGCGVSGEV GGHHVEVGKP SWITRTTPCH DAALVSARLD
560 570 580 590 600
GESRGETVVF VSVDGVVRAA LTIADTLKDS AAAAVAALRS RGLRTILLTG
610 620 630 640 650
DNRAAADAVA AQVGIDSAVA DMLPEGKVDV IQRLREEGHT VAMVGDGIND
660 670 680 690 700
GPALVGADLG LAIGRGTDVA LGAADIILVR DDLNTVPQAL DLARATMRTI
710 720 730 740 750
RMNMIWAFGY NVAAIPIAAA GLLNPLIAGA AMAFSSFFVV SNSLRLRNFG

AQ
Length:752
Mass (Da):77,509
Last modified:July 10, 2007 - v1
Checksum:i21563FE4B4407505
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA Translation: ABQ71827.1
RefSeqiWP_009935939.1, NZ_CP016972.1

Genome annotation databases

EnsemblBacteriaiABQ71827; ABQ71827; MRA_0108
KEGGimra:MRA_0108

Similar proteinsi

Entry informationi

Entry nameiA5TYH7_MYCTA
AccessioniPrimary (citable) accession number: A5TYH7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 25, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health