Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cation transporter p-type ATPase A

Gene

ctpA

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-100-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Cation transporter p-type ATPase AImported
Gene namesi
Name:ctpAImported
Ordered Locus Names:MRA_0096Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001988 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei98 – 12427HelicalUniRule annotationAdd
BLAST
Transmembranei130 – 14920HelicalUniRule annotationAdd
BLAST
Transmembranei161 – 18424HelicalUniRule annotationAdd
BLAST
Transmembranei204 – 22320HelicalUniRule annotationAdd
BLAST
Transmembranei361 – 38020HelicalUniRule annotationAdd
BLAST
Transmembranei386 – 40722HelicalUniRule annotationAdd
BLAST
Transmembranei693 – 71119HelicalUniRule annotationAdd
BLAST
Transmembranei717 – 73519HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi419947.MtubH3_010100022333.

Structurei

3D structure databases

ProteinModelPortaliA5TYG5.
SMRiA5TYG5. Positions 14-79, 101-740.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 7965HMAInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili337 – 36125Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation
Contains 1 HMA domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG2217. LUCA.
HOGENOMiHOG000250397.
KOiK12949.
OMAiGIFLKGH.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR000579. Cation-trans_P-type_ATPase_A/B.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HMA_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
[Graphical view]
PRINTSiPR00940. CATPATPASEA.
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5TYG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTAVTGEHH ASVQRIQLRI SGMSCSACAH RVESTLNKLP GVRAAVNFGT
60 70 80 90 100
RVATIDTSEA VDAAALCQAV RRAGYQADLC TDDGRSASDP DADHARQLLI
110 120 130 140 150
RLAIAAVLFV PVADLSVMFG VVPATRFTGW QWVLSALALP VVTWAAWPFH
160 170 180 190 200
RVAMRNARHH AASMETLISV GITAATIWSL YTVFGNHSPI ERSGIWQALL
210 220 230 240 250
GSDAIYFEVA AGVTVFVLVG RYFEARAKSQ AGSALRALAA LSAKEVAVLL
260 270 280 290 300
PDGSEMVIPA DELKEQQRFV VRPGQIVAAD GLAVDGSAAV DMSAMTGEAK
310 320 330 340 350
PTRVRPGGQV IGGTTVLDGR LIVEAAAVGA DTQFAGMVRL VEQAQAQKAD
360 370 380 390 400
AQRLADRISS VFVPAVLVIA ALTAAGWLIA GGQPDRAVSA ALAVLVIACP
410 420 430 440 450
CALGLATPTA MMVASGRGAQ LGIFLKGYKS LEATRAVDTV VFDKTGTLTT
460 470 480 490 500
GRLQVSAVTA APGWEADQVL ALAATVEAAS EHSVALAIAA ATTRRDAVTD
510 520 530 540 550
FRAIPGRGVS GTVSGRAVRV GKPSWIGSSS CHPNMRAARR HAESLGETAV
560 570 580 590 600
FVEVDGEPCG VIAVADAVKD SARDAVAALA DRGLRTMLLT GDNPESAAAV
610 620 630 640 650
ATRVGIDEVI ADILPEGKVD VIEQLRDRGH VVAMVGDGIN DGPALARADL
660 670 680 690 700
GMAIGRGTDV AIGAADIILV RDHLDVVPLA LDLARATMRT VKLNMVWAFG
710 720 730 740 750
YNIAAIPVAA AGLLNPLVAG AAMAFSSFFV VSNSLRLRKF GRYPLGCGTV
760
GGPQMTAPSS A
Length:761
Mass (Da):78,851
Last modified:July 10, 2007 - v1
Checksum:iD397901EC5C513BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71815.1.
RefSeqiWP_003899808.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ71815; ABQ71815; MRA_0096.
KEGGimra:MRA_0096.
PATRICi18139769. VBIMycTub106795_0106.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71815.1.
RefSeqiWP_003899808.1. NC_009525.1.

3D structure databases

ProteinModelPortaliA5TYG5.
SMRiA5TYG5. Positions 14-79, 101-740.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MtubH3_010100022333.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ71815; ABQ71815; MRA_0096.
KEGGimra:MRA_0096.
PATRICi18139769. VBIMycTub106795_0106.

Phylogenomic databases

eggNOGiCOG2217. LUCA.
HOGENOMiHOG000250397.
KOiK12949.
OMAiGIFLKGH.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-100-MONOMER.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR000579. Cation-trans_P-type_ATPase_A/B.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HMA_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
[Graphical view]
PRINTSiPR00940. CATPATPASEA.
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA5TYG5_MYCTA
AccessioniPrimary (citable) accession number: A5TYG5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.