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Protein
Submitted name:

2-nitropropane dioxygenase

Gene

MRA_0023

Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. dioxygenase activity Source: UniProtKB-KW
  2. nitronate monooxygenase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DioxygenaseImported, Oxidoreductase

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-26-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-nitropropane dioxygenaseImported
Gene namesi
Ordered Locus Names:MRA_0023Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)Imported
Taxonomic identifieri419947 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001988 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi419947.MRA_0023.

Structurei

3D structure databases

SMRiA5TY91. Positions 3-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2070.
HOGENOMiHOG000123285.
KOiK00459.
OMAiRVGCGFI.
OrthoDBiEOG65F8RF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR004136. 2Npropane_dOase.
IPR013785. Aldolase_TIM.
[Graphical view]
PfamiPF03060. NMO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5TY91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSTAFSQM FGIDYPIVSA PMDLIAGGEL AAAVSGAGGL GLIGGGYGDR
60 70 80 90 100
DWLARQFDLA AGAPVGCGFI TWSLARQPQL LDLALQYEPV AVMLSFGDPA
110 120 130 140 150
VFADAIKSAG TRLVCQIQNR TQAERALQVG ADVLVAQGTE AGGHGHGPRS
160 170 180 190 200
TLTLVPEIVD LVTARGTDIP VIAAGGIADG RGLAAALMLG AAGVLVGTRF
210 220 230 240 250
YATVEALSTP QARDPLLAAT GDDMCRTTIY DQLRRYPWPQ GHTMSVLSNA
260 270 280 290 300
LTDQFEDTEL DILHREEAMA RYWRAVAARD YSIANVTAGQ AAGLVNAVLP
310 320
AADVITGMAQ QAARTLTAMR AV
Length:322
Mass (Da):33,568
Last modified:July 10, 2007 - v1
Checksum:iF5B23DFDE92FE6F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71741.1.
RefSeqiYP_001281303.1. NC_009525.1.

Genome annotation databases

EnsemblBacteriaiABQ71741; ABQ71741; MRA_0023.
KEGGimra:MRA_0023.
PATRICi18139610. VBIMycTub106795_0027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000611 Genomic DNA. Translation: ABQ71741.1.
RefSeqiYP_001281303.1. NC_009525.1.

3D structure databases

SMRiA5TY91. Positions 3-316.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419947.MRA_0023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ71741; ABQ71741; MRA_0023.
KEGGimra:MRA_0023.
PATRICi18139610. VBIMycTub106795_0027.

Phylogenomic databases

eggNOGiCOG2070.
HOGENOMiHOG000123285.
KOiK00459.
OMAiRVGCGFI.
OrthoDBiEOG65F8RF.

Enzyme and pathway databases

BioCyciMTUB419947:GJ8N-26-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR004136. 2Npropane_dOase.
IPR013785. Aldolase_TIM.
[Graphical view]
PfamiPF03060. NMO. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv."
    Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L., Wang H., Wang S., Zhao G., Zhang Y.
    PLoS ONE 3:E2375-E2375(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25177 / H37RaImported.

Entry informationi

Entry nameiA5TY91_MYCTA
AccessioniPrimary (citable) accession number: A5TY91
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 1, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.