A5TY84 (A5TY84_MYCTA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine protein kinase EMBL ABQ71734.1

Gene names

Name:	pknB EMBL ABQ71734.1
Ordered Locus Names:	MRA_0016

Organism

Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [Complete proteome] [HAMAP]

Taxonomic identifier

419947 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	626 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase EMBL ABQ71734.1 Transferase
Technical term	3D-structure PDB 3ORT PDB 3ORI PDB 3ORK PDB 3ORL PDB 3ORM PDB 3ORO PDB 3ORP Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW penicillin binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5TY84 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 6C27EEBE9D5A453B	FASTA	626	66,510
	10 20 30 40 50 60 MTTPSHLSDR YELGEILGFG GMSEVHLARD LRLHRDVAVK VLRADLARDP SFYLRFRREA 70 80 90 100 110 120 QNAAALNHPA IVAVYDTGEA ETPAGPLPYI VMEYVDGVTL RDIVHTEGPM TPKRAIEVIA 130 140 150 160 170 180 DACQALNFSH QNGIIHRDVK PANIMISATN AVKVMDFGIA RAIADSGNSV TQTAAVIGTA 190 200 210 220 230 240 QYLSPEQARG DSVDARSDVY SLGCVLYEVL TGEPPFTGDS PVSVAYQHVR EDPIPPSARH 250 260 270 280 290 300 EGLSADLDAV VLKALAKNPE NRYQTAAEMR ADLVRVHNGE PPEAPKVLTD AERTSLLSSA 310 320 330 340 350 360 AGNLSGPRTD PLPRQDLDDT DRDRSIGSVG RWVAVVAVLA VLTVVVTIAI NTFGGITRDV 370 380 390 400 410 420 QVPDVRGQSS ADAIATLQNR GFKIRTLQKP DSTIPPDHVI GTDPAANTSV SAGDEITVNV 430 440 450 460 470 480 STGPEQREIP DVSTLTYAEA VKKLTAAGFG RFKQANSPST PELVGKVIGT NPPANQTSAI 490 500 510 520 530 540 TNVVIIIVGS GPATKDIPDV AGQTVDVAQK NLNVYGFTKF SQASVDSPRP AGEVTGTNPP 550 560 570 580 590 600 AGTTVPVDSV IELQVSKGNQ FVMPDLSGMF WVDAEPRLRA LGWTGMLDKG ADVDAGGSQH 610 620 NRVVYQNPPA GTGVNRDGII TLRFGQ

References

[1]

"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv." Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000611 Genomic DNA. Translation: ABQ71734.1.

RefSeq

YP_001281296.1. NC_009525.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3ORI	X-ray	2.00	A/B/C/D	1-308	[»]
3ORK	X-ray	1.60	A	1-308	[»]
3ORL	X-ray	2.90	A	1-308	[»]
3ORM	X-ray	2.50	A	1-308	[»]
3ORO	X-ray	1.90	A	1-308	[»]
3ORP	X-ray	2.10	A	1-308	[»]
3ORT	X-ray	1.90	A	1-308	[»]
3OUV	X-ray	2.00	A	491-558	[»]

ProteinModelPortal

A5TY84.

SMR

A5TY84. Positions 1-286.

ModBase

Search...

Protein-protein interaction databases

STRING

A5TY84.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBMYCT00000068170; EBMYCP00000066280; EBMYCG00000068165.

GeneID

5212134.

GenomeReviews

Gene locus MRA_0016 in contig CP000611_GR.

KEGG

mra:MRA_0016.

PATRIC

18139594. VBIMycTub106795_0020.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG0515.

GeneTree

EBGT00050000014804.

HOGENOM

HBG755340.

OMA

TDTGKDP.

ProtClustDB

CLSK790192.

Family and domain databases

InterPro

IPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR017442. Se/Thr_kinase-like_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR002290. Ser/Thr_kinase_dom.
[Graphical view]

KO

K08884.

Pfam

PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]

SMART

SM00740. PASTA. 4 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]

SUPFAM

SSF56112. Kinase_like. 1 hit.

PROSITE

PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

A5TY84_MYCTA

Accession

Primary (citable) accession number: A5TY84

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)