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A5TNF9

- A5TNF9_BURML

UniProt

A5TNF9 - A5TNF9_BURML

Protein

Pyruvate dehydrogenase E1 component

Gene

BMA721280_I0360

Organism
Burkholderia mallei 2002721280
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (10 Jul 2007)
      Previous versions | rss
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    Functioni

    Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.UniRule annotation

    Cofactori

    Thiamine pyrophosphate.UniRule annotation

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    PyruvateUniRule annotation, Thiamine pyrophosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 componentUniRule annotation (EC:1.2.4.1UniRule annotation)
    Gene namesi
    ORF Names:BMA721280_I0360Imported
    OrganismiBurkholderia mallei 2002721280Imported
    Taxonomic identifieri370895 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

    Structurei

    3D structure databases

    ProteinModelPortaliA5TNF9.
    SMRiA5TNF9. Positions 69-897.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.920. 1 hit.
    3.40.50.970. 2 hits.
    InterProiIPR004660. 2-oxoA_DH_E1.
    IPR017600. Alpha-ketoglut_DH.
    IPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005474. Transketolase_N.
    [Graphical view]
    PfamiPF00456. Transketolase_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000156. Pyruvate_dh_E1. 1 hit.
    SUPFAMiSSF52518. SSF52518. 2 hits.
    SSF52922. SSF52922. 1 hit.
    TIGRFAMsiTIGR00759. aceE. 1 hit.
    TIGR03186. AKGDH_not_PDH. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5TNF9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNDLSNGIRP VLATARRHDD TDPQETAEWL DALDGVVAHA GAERAQYLLA    50
    QLAEHAARRR LAPPHAGATP YVNTIPVDEE PPYPGDLQLE ERLAAVLRWN 100
    ALAMVVRANR AYGELGGHIA SYASAADLFE VGFNHFFRAA GDASGGDLVY 150
    FQPHSSPGVY ARAFLEGFLS DAQLEHYRRE IAGPGLCSYP HPWLMPDFWQ 200
    FPTGSMGIGP INAIYQARFM RYLQNRGLLR TEGRKVWGFF GDGEMDEPES 250
    IGALSLAARE GLDNLVFVIN CNLQRLDGPV RGNGRIVDEL ESQFAGAGWN 300
    VIKVLWGSDW DALFARDATG ALARAFAQTV DGQFQTFSAN DGAYNRARFF 350
    GQNDALAALV AHLRDEDIDR LRRGGHDARK LYAAYERAVR HEGRPTVILA 400
    KTMKGFGLGA IGQGRMTTHQ QKKLDVEHLL AFRDRFRLPL TDEDVAQLRF 450
    YRPEKDSPEM RYLHARRAAL GGCLPRRRAA ATAALTVPSL PSWGQFALDG 500
    GREMSTTMAI VRMLGGLLKD AALGPRIVPI VADEARTFGM ANLFRQVGIY 550
    SPLGQRYEPE DLGSMLYYRE DTRGQILEEG ISEAGAISSW IAAATSYSVH 600
    DLPMLPFYIY YSMFGFQRIG DLIWAAADQR ARGFLIGATS GKTTLGGEGL 650
    QHQDGTSHLA ASTVPNCRAW DPAFAYEIAV IVDEGMREMV ERQRDTFYYL 700
    TVTNENHAQP TLPADRLDAV RGGILKGMYP LDAAALPAAR VQLLGSGAIL 750
    GEVQAAARLL RDDWRIDAAV WSVTSFTELQ RDGIAAERAQ RLFDADDANE 800
    RSPTPHVTSA LAATQGPVIA ATDYARALPE LIRAYVPRRY VTLGTDGFGR 850
    SDTREALRAF FEVDRGSIVI AALRALADDG EVTRTVVRDA IARYGKRDAS 900
    RTPPWER 907
    Length:907
    Mass (Da):99,904
    Last modified:July 10, 2007 - v1
    Checksum:iF9297894299BDEEA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH899695 Genomic DNA. Translation: EDK86428.1.

    Genome annotation databases

    EnsemblBacteriaiEDK86428; EDK86428; BMA721280_I0360.
    PATRICi26895019. VBIBurMal4978_4497.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH899695 Genomic DNA. Translation: EDK86428.1 .

    3D structure databases

    ProteinModelPortali A5TNF9.
    SMRi A5TNF9. Positions 69-897.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EDK86428 ; EDK86428 ; BMA721280_I0360 .
    PATRICi 26895019. VBIBurMal4978_4497.

    Family and domain databases

    Gene3Di 3.40.50.920. 1 hit.
    3.40.50.970. 2 hits.
    InterProi IPR004660. 2-oxoA_DH_E1.
    IPR017600. Alpha-ketoglut_DH.
    IPR029061. THDP-binding.
    IPR009014. Transketo_C/Pyr-ferredox_oxred.
    IPR005474. Transketolase_N.
    [Graphical view ]
    Pfami PF00456. Transketolase_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000156. Pyruvate_dh_E1. 1 hit.
    SUPFAMi SSF52518. SSF52518. 2 hits.
    SSF52922. SSF52922. 1 hit.
    TIGRFAMsi TIGR00759. aceE. 1 hit.
    TIGR03186. AKGDH_not_PDH. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Annotation of Burkholderia mallei 2002721280."
      DeShazer D., Woods D.E., Nierman W.C.
      Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 2002721280Imported.

    Entry informationi

    Entry nameiA5TNF9_BURML
    AccessioniPrimary (citable) accession number: A5TNF9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 10, 2007
    Last sequence update: July 10, 2007
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)