Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A5TNF9 (A5TNF9_BURML) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component PIRNR PIRNR000156

EC=1.2.4.1 PIRNR PIRNR000156
Gene names
ORF Names:BMA721280_I0360 EMBL EDK86428.1
OrganismBurkholderia mallei 2002721280 EMBL EDK86428.1
Taxonomic identifier370895 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length907 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. PIRNR PIRNR000156

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2. PIRNR PIRNR000156

Cofactor

Thiamine pyrophosphate By similarity. PIRNR PIRNR000156

Sequences

Sequence LengthMass (Da)Tools
A5TNF9 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: F9297894299BDEEA

FASTA90799,904
        10         20         30         40         50         60 
MNDLSNGIRP VLATARRHDD TDPQETAEWL DALDGVVAHA GAERAQYLLA QLAEHAARRR 

        70         80         90        100        110        120 
LAPPHAGATP YVNTIPVDEE PPYPGDLQLE ERLAAVLRWN ALAMVVRANR AYGELGGHIA 

       130        140        150        160        170        180 
SYASAADLFE VGFNHFFRAA GDASGGDLVY FQPHSSPGVY ARAFLEGFLS DAQLEHYRRE 

       190        200        210        220        230        240 
IAGPGLCSYP HPWLMPDFWQ FPTGSMGIGP INAIYQARFM RYLQNRGLLR TEGRKVWGFF 

       250        260        270        280        290        300 
GDGEMDEPES IGALSLAARE GLDNLVFVIN CNLQRLDGPV RGNGRIVDEL ESQFAGAGWN 

       310        320        330        340        350        360 
VIKVLWGSDW DALFARDATG ALARAFAQTV DGQFQTFSAN DGAYNRARFF GQNDALAALV 

       370        380        390        400        410        420 
AHLRDEDIDR LRRGGHDARK LYAAYERAVR HEGRPTVILA KTMKGFGLGA IGQGRMTTHQ 

       430        440        450        460        470        480 
QKKLDVEHLL AFRDRFRLPL TDEDVAQLRF YRPEKDSPEM RYLHARRAAL GGCLPRRRAA 

       490        500        510        520        530        540 
ATAALTVPSL PSWGQFALDG GREMSTTMAI VRMLGGLLKD AALGPRIVPI VADEARTFGM 

       550        560        570        580        590        600 
ANLFRQVGIY SPLGQRYEPE DLGSMLYYRE DTRGQILEEG ISEAGAISSW IAAATSYSVH 

       610        620        630        640        650        660 
DLPMLPFYIY YSMFGFQRIG DLIWAAADQR ARGFLIGATS GKTTLGGEGL QHQDGTSHLA 

       670        680        690        700        710        720 
ASTVPNCRAW DPAFAYEIAV IVDEGMREMV ERQRDTFYYL TVTNENHAQP TLPADRLDAV 

       730        740        750        760        770        780 
RGGILKGMYP LDAAALPAAR VQLLGSGAIL GEVQAAARLL RDDWRIDAAV WSVTSFTELQ 

       790        800        810        820        830        840 
RDGIAAERAQ RLFDADDANE RSPTPHVTSA LAATQGPVIA ATDYARALPE LIRAYVPRRY 

       850        860        870        880        890        900 
VTLGTDGFGR SDTREALRAF FEVDRGSIVI AALRALADDG EVTRTVVRDA IARYGKRDAS 


RTPPWER 

« Hide

References

[1]"Annotation of Burkholderia mallei 2002721280."
DeShazer D., Woods D.E., Nierman W.C.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 2002721280 EMBL EDK86428.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH899695 Genomic DNA. Translation: EDK86428.1.

3D structure databases

ProteinModelPortalA5TNF9.
SMRA5TNF9. Positions 69-897.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEDK86428; EDK86428; BMA721280_I0360.
PATRIC26895019. VBIBurMal4978_4497.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
3.40.50.970. 2 hits.
InterProIPR004660. 2-oxoA_DH_E1.
IPR017600. Alpha-ketoglut_DH.
IPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005474. Transketolase_N.
[Graphical view]
PfamPF00456. Transketolase_N. 1 hit.
[Graphical view]
PIRSFPIRSF000156. Pyruvate_dh_E1. 1 hit.
SUPFAMSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsTIGR00759. aceE. 1 hit.
TIGR03186. AKGDH_not_PDH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5TNF9_BURML
AccessionPrimary (citable) accession number: A5TNF9
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)