A5THT6 (A5THT6_BURMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:	aroB HAMAP MF_00110 EMBL EDK84455.1
ORF Names:	BMA721280_E0398 EMBL EDK84455.1

Organism

Burkholderia mallei 2002721280 EMBL EDK84455.1

Taxonomic identifier

370895 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL EDK84455.1
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5THT6 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: CFD37136057BD086	FASTA	359	37,896
	10 20 30 40 50 60 MITVNVDLGE RAYPIHIGAD LIGRTELFAP HIAGASVTIV TNTTVEPLYG DTLRAALAPL 70 80 90 100 110 120 GKRVSTVVLP DGEAYKNWET LNLIFDGLLE QHADRKTTLI ALGGGVIGDM TGFAAACYMR 130 140 150 160 170 180 GVPFIQVPTT LLSQVDSSVG GKTGINHPLG KNMIGAFYQP QAVIADIGAL STLPDRELAA 190 200 210 220 230 240 GVAEIVKTGA IADAAFFDWI EANVGALTRR DPDALAHAVK RSCEIKAGVV AADEREGGLR 250 260 270 280 290 300 AILNFGHTFG HAIEAGLGYG EWLHGEAVGC GMVMAADLSV RTGHLDEASR ARLCRVVEAA 310 320 330 340 350 HLPTRAPDLG DARYVELMRV DKKAEAGAIK FILLKRFGET IITPAPDDAV LATLAATTR

References

[1]	"Annotation of Burkholderia mallei 2002721280." DeShazer D., Woods D.E., Nierman W.C. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 2002721280 EMBL EDK84455.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH899693 Genomic DNA. Translation: EDK84455.1.
3D structure databases
ProteinModelPortal	A5THT6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26890584. VBIBurMal4978_1848.
Phylogenomic databases
OMA	VMALEMS.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5THT6_BURMA

Accession

Primary (citable) accession number: A5THT6

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)