Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

NOP2/Sun RNA methyltransferase family, member 2

Gene

nsun2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei209S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei236S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei262S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei315NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, RNA-bindingPROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NOP2/Sun RNA methyltransferase family, member 2Imported
Gene namesi
Name:nsun2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-030131-4017 nsun2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiA5PMI3
PeptideAtlasiA5PMI3

Expressioni

Gene expression databases

BgeeiENSDARG00000056665
ExpressionAtlasiA5PMI3 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000118997

Structurei

3D structure databases

ProteinModelPortaliA5PMI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 424SAM_MT_RSMB_NOPInterPro annotationAdd BLAST365

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni178 – 184S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili718 – 738Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2198 Eukaryota
COG0144 LUCA
GeneTreeiENSGT00660000095589
HOGENOMiHOG000205147
HOVERGENiHBG106711
InParanoidiA5PMI3
OMAiTFVRCEN
OrthoDBiEOG091G04FO
PhylomeDBiA5PMI3
TreeFamiTF300702

Family and domain databases

InterProiView protein in InterPro
IPR001678 MeTrfase_RsmB/NOP2
IPR023267 RCMT
IPR023270 RCMT_NCL1
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PRINTSiPR02008 RCMTFAMILY
PR02011 RCMTNCL1
SUPFAMiSSF53335 SSF53335, 2 hits
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

A5PMI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRNKNRPQ QYRDGRPEGK RSRDDAAWGA GYADIVKENK LFEHYYQELK
60 70 80 90 100
IVPDGEFEEF MEAMREPLPA TIRITGYKSH AKEILHTLKE KYFKEVQDLE
110 120 130 140 150
VDGQKIEAPQ PLSWYPDELA WHTNLSRKIL RKSPLLEKFH QFLVSETESG
160 170 180 190 200
NISRQEAVSM IPPLLLKIEP QHKILDMCAA PGSKTAQLIE MLHSDMDVPF
210 220 230 240 250
PEGFVIANDV DNKRCYLLVH QAKRLNSPCI MVVNHDASSI PRLHFDNNGK
260 270 280 290 300
KDILFYDRIL CDVPCSGDGT MRKNIDVWKK WTTSNSLHLH GLQLRIAVRG
310 320 330 340 350
VEQLAVGGRM VYSTCSLNPI EDEAVIAALL EKSEGSLELA DASPDLPGLK
360 370 380 390 400
YMPGITSWKV MTKEGQWFSN FSEVPTSRHT QIRPTMFPPS DSEKLTEMRL
410 420 430 440 450
ERCVRILPHH QNTGGFFVAV LVKKAPMPWN RRHPKLRNKE VSSSGEVAPV
460 470 480 490 500
EELQMDESPT DVPPADGPST DAPVEEGERN PSVPETPEPV EVKKENVCGP
510 520 530 540 550
PPPKKMKLFG FKEDPFVFLT EDDPIFPPIQ SFYDLSPDFP KLNVLTRTHE
560 570 580 590 600
GKKRHLYMVS KELRNVLLNN SERMKVINTG VKVLSRNNDG EQFGCAFRLA
610 620 630 640 650
QEGVYTLCPY IRARIINISV EDVKVLLTQE NPFLSKLGDE AHMQAKKLEM
660 670 680 690 700
GSIVLRYLPD PKDLDAPQCP IDLCGWRGKT SIRAFVSRNE RLHYLRMVGV
710 720 730 740 750
EVFRDKQGKR NDGQTETQEE STEDAEGLSQ EVDLVEQEGA ETEKSSSESN
760
PNGTELVSST CDGSTS
Length:766
Mass (Da):86,714
Last modified:July 10, 2007 - v1
Checksum:i9D927A6CC2FA2970
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX511155 Genomic DNA No translation available.
RefSeqiXP_005170060.1, XM_005170003.3
UniGeneiDr.119317

Genome annotation databases

EnsembliENSDART00000140336; ENSDARP00000118997; ENSDARG00000056665
GeneIDi325292

Similar proteinsi

Entry informationi

Entry nameiA5PMI3_DANRE
AccessioniPrimary (citable) accession number: A5PMI3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health