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Protein
Submitted name:

Zgc:165629 protein

Gene

ccr7

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. C-C chemokine receptor activity Source: InterPro
  2. C-X-C chemokine receptor activity Source: InterPro

GO - Biological processi

  1. chemotaxis Source: InterPro
  2. immune response Source: InterPro
  3. inflammatory response Source: InterPro
  4. neutrophil activation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Zgc:165629 proteinImported
Gene namesi
Name:ccr7Imported
ORF Names:zgc:165629Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-060522-2. ccr7.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065440.

Structurei

3D structure databases

ProteinModelPortaliA5PLI3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG149643.
HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04182.
PhylomeDBiA5PLI3.

Family and domain databases

InterProiIPR001718. Chemokine_CCR7.
IPR001277. Chemokine_CXCR4.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24227. PTHR24227. 1 hit.
PTHR24227:SF29. PTHR24227:SF29. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR00645. CXCCHMKINER4.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5PLI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHAYTVFCPV LLIWSCHIKK SWSNMTEHQM GEKATTEYDY TTGTVDYDIY
60 70 80 90 100
EQSCNKTNNR TFRAWFLPTI YTIICLLALM GNFLVILTYL YFKRLKTMTD
110 120 130 140 150
VYLFNLAMAD LLFAISLPFW AASFMSTWHL GLYPCKAMFT IYKVSFFSGM
160 170 180 190 200
FLLTCISIDR YFSITKAVSA HRCRSSAVYY GQVSSLVTWV IAIVFSVPDM
210 220 230 240 250
VFAVINSRGT CSANVNYQDY YVKMVISQMV LGFIIPAVVM GFCYICIIKT
260 270 280 290 300
LMQAKNFERN KAFKVIIAVV VVFVFSQLPY NVVMGVSVQQ TTDCAKDNTR
310 320 330 340 350
LFALDVTMAV AFLRCCVNPF LYAFIGVKFR NDLLKLLKDL GCLRTSHLMY
360 370
THCGRRRSSV GLDTETTTTF SP
Length:372
Mass (Da):42,515
Last modified:July 10, 2007 - v1
Checksum:i91F76238586FF0DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142913 mRNA. Translation: AAI42914.1.
RefSeqiNP_001092213.1. NM_001098743.1.
UniGeneiDr.90195.

Genome annotation databases

GeneIDi565958.
KEGGidre:565958.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142913 mRNA. Translation: AAI42914.1.
RefSeqiNP_001092213.1. NM_001098743.1.
UniGeneiDr.90195.

3D structure databases

ProteinModelPortaliA5PLI3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065440.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi565958.
KEGGidre:565958.

Organism-specific databases

CTDi1236.
ZFINiZDB-GENE-060522-2. ccr7.

Phylogenomic databases

eggNOGiNOG149643.
HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04182.
PhylomeDBiA5PLI3.

Miscellaneous databases

NextBioi20887942.

Family and domain databases

InterProiIPR001718. Chemokine_CCR7.
IPR001277. Chemokine_CXCR4.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24227. PTHR24227. 1 hit.
PTHR24227:SF29. PTHR24227:SF29. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR00645. CXCCHMKINER4.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Olfactory epitheliumImported.

Entry informationi

Entry nameiA5PLI3_DANRE
AccessioniPrimary (citable) accession number: A5PLI3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: January 7, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.