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Protein
Submitted name:

Zgc:165629 protein

Gene

ccr7

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • chemokine receptor activity Source: InterPro
  • G-protein coupled receptor activity Source: ZFIN

GO - Biological processi

  • chemotaxis Source: InterPro
  • dorsal/ventral pattern formation Source: ZFIN
  • negative regulation of canonical Wnt signaling pathway Source: ZFIN

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Zgc:165629 proteinImported
Gene namesi
Name:ccr7Imported
ORF Names:zgc:165629Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-060522-2 ccr7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 90HelicalSequence analysisAdd BLAST26
Transmembranei102 – 121HelicalSequence analysisAdd BLAST20
Transmembranei141 – 162HelicalSequence analysisAdd BLAST22
Transmembranei183 – 205HelicalSequence analysisAdd BLAST23
Transmembranei225 – 251HelicalSequence analysisAdd BLAST27
Transmembranei263 – 282HelicalSequence analysisAdd BLAST20
Transmembranei302 – 325HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500268541324 – 372Sequence analysisAdd BLAST349

Structurei

3D structure databases

ProteinModelPortaliA5PLI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 322G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IMBE Eukaryota
ENOG4110ZGY LUCA
HOGENOMiHOG000234122
HOVERGENiHBG106917
KOiK04182
PhylomeDBiA5PLI3

Family and domain databases

InterProiView protein in InterPro
IPR000355 Chemokine_rcpt
IPR001277 CXCR4/ACKR2
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00657 CCCHEMOKINER
PR00645 CXCCHMKINER4
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A5PLI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHAYTVFCPV LLIWSCHIKK SWSNMTEHQM GEKATTEYDY TTGTVDYDIY
60 70 80 90 100
EQSCNKTNNR TFRAWFLPTI YTIICLLALM GNFLVILTYL YFKRLKTMTD
110 120 130 140 150
VYLFNLAMAD LLFAISLPFW AASFMSTWHL GLYPCKAMFT IYKVSFFSGM
160 170 180 190 200
FLLTCISIDR YFSITKAVSA HRCRSSAVYY GQVSSLVTWV IAIVFSVPDM
210 220 230 240 250
VFAVINSRGT CSANVNYQDY YVKMVISQMV LGFIIPAVVM GFCYICIIKT
260 270 280 290 300
LMQAKNFERN KAFKVIIAVV VVFVFSQLPY NVVMGVSVQQ TTDCAKDNTR
310 320 330 340 350
LFALDVTMAV AFLRCCVNPF LYAFIGVKFR NDLLKLLKDL GCLRTSHLMY
360 370
THCGRRRSSV GLDTETTTTF SP
Length:372
Mass (Da):42,515
Last modified:July 10, 2007 - v1
Checksum:i91F76238586FF0DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142913 mRNA Translation: AAI42914.1
RefSeqiNP_001092213.1, NM_001098743.1
UniGeneiDr.90195

Genome annotation databases

GeneIDi565958
KEGGidre:565958

Similar proteinsi

Entry informationi

Entry nameiA5PLI3_DANRE
AccessioniPrimary (citable) accession number: A5PLI3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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