Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

HDAC6 protein

Gene

HDAC6

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HDAC6 proteinImported
Gene namesi
Name:HDAC6Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000050519.

Structurei

3D structure databases

ProteinModelPortaliA5PJZ7.
SMRiA5PJZ7. Positions 1023-1127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0123.
HOGENOMiHOG000004769.
HOVERGENiHBG051894.
KOiK11407.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
SMARTiSM00290. ZnF_UBP. 1 hit.
[Graphical view]
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5PJZ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSTGQDSTT PKERRSRHNP HSPTHDSSIT SKRGVKKSAI LRSSPSLAEV
60 70 80 90 100
KKKGRMKKLS QTAEQDLIMG LQGLNLNLES RTLSGTGLVF DEQLNEFHCL
110 120 130 140 150
WDDSFPERPE RLHAIKEQLI QEGLLDRCVS FQARFAEKEE LMLVHSLEYI
160 170 180 190 200
DLMETTQYMN EEELHVLADT YDSVYLHPNS YTCACLASGS VLRLVDAVLE
210 220 230 240 250
AEIRNGMAII RPPGHHAQHS LMDGYCMFNH VAVAARYAQQ KHDIQRVLIV
260 270 280 290 300
DWDVHHGQGI QFAFDQDPSV LYFSIHRYEQ GRFWPHLKAS NWSTTGLGQG
310 320 330 340 350
QGYTINVPWN QVGMQDADYI AAFLHVLLPV AFEFQPQLVL VAAGFDALQG
360 370 380 390 400
DPKGEMAATP AGFAQLTHLL MGLAEGKLIL SLEGGYNLHS LAEGVSATLH
410 420 430 440 450
TLLGDPCPVL ESPGAPCPSA QASLSCTLEA LEPFWESLVR SVESLEEKDT
460 470 480 490 500
VEKDDVEEKE EERLPQSPEL SVPIWPVLQA RTGLVYDQQM MDHHNLWDNY
510 520 530 540 550
HPEMPQRIHF IMHHLDELGL AKRCHSLPAR PATDAELLTC HSAEHLERLR
560 570 580 590 600
ATEKMKTREL RREGANYDSI YICSSTFACA QLAAGAACRL VEAVLAGEVL
610 620 630 640 650
NGVAVVRPPG HHAEPDAACG FCFFNSVAVA ARHAQAISGH ALRILIVDWD
660 670 680 690 700
IHHGNGTQHI FEEDPSVLYI SLHRYDHGTF FPMGNEGACT RIGKATGTGF
710 720 730 740 750
TVNVAWNGPR MGDADYLAAW HRLVLPVAYE FNPELVLVSA GFDAARGDPL
760 770 780 790 800
GGCQVSPEGY AHLTHQLMGL ANGHIILILE GGYNLTSISE SMAACTRSLL
810 820 830 840 850
GDPLPLLTRL RPPLSGAQAS ITKTIQVHRR YWRSLRVMKR KNKEELSSSK
860 870 880 890 900
LITKKPSQPA SPGLANVTTT VEGNILETGM GQAASEASVK ESTPDQTESA
910 920 930 940 950
TAPVELTQGQ SSDTATQGAA LDQTISEGAT GGAELIQNPP ASCINNRIPP
960 970 980 990 1000
ALPVQGATAQ TSPSKLMANL RILDLDSTTQ EPSEEEGLLG EAAGGQDTNE
1010 1020 1030 1040 1050
SVPVQVFGDH ADTDEVMFYA VRPLLWCPHL AAVCPIPETG LNVTQPCQYC
1060 1070 1080 1090 1100
GTLQENWVCL SCYQVYCGRY INAHMLQHHE GSGHPLVLSY ADLSAWCYHC
1110 1120
QAYVHHKDLL AVKNIAHQNK FGEDIPHSD
Length:1,129
Mass (Da):123,975
Last modified:July 10, 2007 - v1
Checksum:iC11FD28F15597D13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142298 mRNA. Translation: AAI42299.1.
RefSeqiNP_001092430.1. NM_001098960.1.
UniGeneiBt.76413.

Genome annotation databases

GeneIDi513602.
KEGGibta:513602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142298 mRNA. Translation: AAI42299.1.
RefSeqiNP_001092430.1. NM_001098960.1.
UniGeneiBt.76413.

3D structure databases

ProteinModelPortaliA5PJZ7.
SMRiA5PJZ7. Positions 1023-1127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000050519.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi513602.
KEGGibta:513602.

Organism-specific databases

CTDi10013.

Phylogenomic databases

eggNOGiCOG0123.
HOGENOMiHOG000004769.
HOVERGENiHBG051894.
KOiK11407.

Miscellaneous databases

NextBioi20870941.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
SMARTiSM00290. ZnF_UBP. 1 hit.
[Graphical view]
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HerefordImported.
    Tissue: ThymusImported.

Entry informationi

Entry nameiA5PJZ7_BOVIN
AccessioniPrimary (citable) accession number: A5PJZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 1, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.