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Protein

Peroxisomal membrane protein 4

Gene

PXMP4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein 4
Gene namesi
Name:PXMP4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136 Componenti: Chromosome 13

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei97 – 11721HelicalSequence AnalysisAdd
BLAST
Transmembranei153 – 17321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. peroxisomal membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 212211Peroxisomal membrane protein 4PRO_0000317317Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051908.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG79127.
GeneTreeiENSGT00390000001562.
HOGENOMiHOG000157771.
HOVERGENiHBG053773.
InParanoidiA5PJL1.
KOiK13350.
OMAiYTHSRNL.
OrthoDBiEOG7NSB3Q.
TreeFamiTF105313.

Family and domain databases

InterProiIPR019531. Pmp4.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]
PIRSFiPIRSF013674. PXMP4. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A5PJL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAPPQLRAL LFAINALLSK RRYHAALAML KGFRNGAVYG AKIRAPHALV
60 70 80 90 100
MTFLFRSGSL REKLRAILQA TYTHSWNLAR FVFLYKGLCA LQSHVQGKTY
110 120 130 140 150
QAHSFVSAFI GGLLVFGNNN NINSQISMYL LSRVLFALCR LGVEKGFIPE
160 170 180 190 200
PRLDPFPWFS GLVWGLVLWL FEYHRPTLQP SLQSSMTYLY EDSNVWHDLS
210
DFFIYNKSQP SK
Length:212
Mass (Da):24,224
Last modified:July 10, 2007 - v1
Checksum:iC8318CECBC6F8911
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142155 mRNA. Translation: AAI42156.1.
RefSeqiNP_001092633.1. NM_001099163.1.
UniGeneiBt.61975.

Genome annotation databases

EnsembliENSBTAT00000053065; ENSBTAP00000051908; ENSBTAG00000038738.
GeneIDi617160.
KEGGibta:617160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142155 mRNA. Translation: AAI42156.1.
RefSeqiNP_001092633.1. NM_001099163.1.
UniGeneiBt.61975.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051908.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000053065; ENSBTAP00000051908; ENSBTAG00000038738.
GeneIDi617160.
KEGGibta:617160.

Organism-specific databases

CTDi11264.

Phylogenomic databases

eggNOGiNOG79127.
GeneTreeiENSGT00390000001562.
HOGENOMiHOG000157771.
HOVERGENiHBG053773.
InParanoidiA5PJL1.
KOiK13350.
OMAiYTHSRNL.
OrthoDBiEOG7NSB3Q.
TreeFamiTF105313.

Miscellaneous databases

NextBioi20900517.

Family and domain databases

InterProiIPR019531. Pmp4.
IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]
PIRSFiPIRSF013674. PXMP4. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Fetal muscle.

Entry informationi

Entry nameiPXMP4_BOVIN
AccessioniPrimary (citable) accession number: A5PJL1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: March 4, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.