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Protein

Leucine-rich repeat-containing protein 14

Gene

LRRC14

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 14
Gene namesi
Name:LRRC14
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 14

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003436801 – 493Leucine-rich repeat-containing protein 14Add BLAST493

Proteomic databases

PaxDbiA5PJJ5.

Expressioni

Gene expression databases

BgeeiENSBTAG00000004969.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006542.

Structurei

3D structure databases

ProteinModelPortaliA5PJJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati285 – 307LRR 1Add BLAST23
Repeati310 – 330LRR 2Add BLAST21
Repeati337 – 360LRR 3Add BLAST24
Repeati366 – 387LRR 4Add BLAST22
Repeati394 – 414LRR 5Add BLAST21

Sequence similaritiesi

Belongs to the PRAME family. LRRC14 subfamily.Curated
Contains 5 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiENOG410IIBA. Eukaryota.
ENOG4111FCX. LUCA.
GeneTreeiENSGT00760000119028.
HOGENOMiHOG000113363.
HOVERGENiHBG052342.
InParanoidiA5PJJ5.
OMAiPILTRCT.
OrthoDBiEOG091G05TB.
TreeFamiTF332708.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR026292. LRRC14.
[Graphical view]
PANTHERiPTHR14224:SF9. PTHR14224:SF9. 1 hit.
PfamiPF13516. LRR_6. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5PJJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTLVFLSTR QVLQCQSAAC QALPLLPREL FPLLFKVAFM DKKTVVLREL
60 70 80 90 100
VHTWPFPLLS FQQLLQECAH CSRALLQERP STESMQAVIL GLTARLHTPE
110 120 130 140 150
TEPGTQPLCR KHTLRVLDMT GLLDDGVEQD PGTMSMWDCT AAVARTCIEQ
160 170 180 190 200
QQGRTAEPGQ APVPVEVRVD LRVNRASYAF LREALRSSVG SPLRLCCRDL
210 220 230 240 250
RAEDLPMRNT VALLQLLDAG CLRRVDLRFN NLGLRGLSVI IPHVARFQHL
260 270 280 290 300
ASLRLHYVHG DSRQPSVDGE DNFRYFLAQM GRFTCLRELS MGSSLLSGRL
310 320 330 340 350
DQLLSTLQSP LESLELAFCA LLPEDLRFLA RSSHAVHLKK LDLSGNDLSG
360 370 380 390 400
SQLEPFQGLL QAAAATLLHL ELTECQLADT QLLATLPVLT RCASLRYLGL
410 420 430 440 450
YGNPLSVAGL RELLRDSVVQ AELRTVVHPF PVDCYEGLPW PPPASVLLEA
460 470 480 490
SINEEKFARV EAELHQLLLA SGRAHVLWTT DIYGRLAADY FSL
Length:493
Mass (Da):54,918
Last modified:July 10, 2007 - v1
Checksum:i9DA2857016814323
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142136 mRNA. Translation: AAI42137.1.
RefSeqiNP_001095849.1. NM_001102379.1.
XP_015329847.1. XM_015474361.1.
XP_015329848.1. XM_015474362.1.
XP_015329849.1. XM_015474363.1.
UniGeneiBt.100306.
Bt.27389.

Genome annotation databases

EnsembliENSBTAT00000006542; ENSBTAP00000006542; ENSBTAG00000004969.
GeneIDi539952.
KEGGibta:539952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142136 mRNA. Translation: AAI42137.1.
RefSeqiNP_001095849.1. NM_001102379.1.
XP_015329847.1. XM_015474361.1.
XP_015329848.1. XM_015474362.1.
XP_015329849.1. XM_015474363.1.
UniGeneiBt.100306.
Bt.27389.

3D structure databases

ProteinModelPortaliA5PJJ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006542.

Proteomic databases

PaxDbiA5PJJ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000006542; ENSBTAP00000006542; ENSBTAG00000004969.
GeneIDi539952.
KEGGibta:539952.

Organism-specific databases

CTDi9684.

Phylogenomic databases

eggNOGiENOG410IIBA. Eukaryota.
ENOG4111FCX. LUCA.
GeneTreeiENSGT00760000119028.
HOGENOMiHOG000113363.
HOVERGENiHBG052342.
InParanoidiA5PJJ5.
OMAiPILTRCT.
OrthoDBiEOG091G05TB.
TreeFamiTF332708.

Gene expression databases

BgeeiENSBTAG00000004969.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR026292. LRRC14.
[Graphical view]
PANTHERiPTHR14224:SF9. PTHR14224:SF9. 1 hit.
PfamiPF13516. LRR_6. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLRC14_BOVIN
AccessioniPrimary (citable) accession number: A5PJJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 10, 2007
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.