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Protein

Translation initiation factor eIF-2B subunit gamma

Gene

EIF2B3

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor eIF-2B subunit gamma
Alternative name(s):
eIF-2B GDP-GTP exchange factor subunit gamma
Gene namesi
Name:EIF2B3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003173311 – 452Translation initiation factor eIF-2B subunit gammaAdd BLAST452

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei261PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PRIDEiA5PJI7

Interactioni

Subunit structurei

Complex of five different subunits; alpha, beta, gamma, delta and epsilon.By similarity

Structurei

3D structure databases

ProteinModelPortaliA5PJI7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000230731
HOVERGENiHBG051461
InParanoidiA5PJI7

Family and domain databases

InterProiView protein in InterPro
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans
PfamiView protein in Pfam
PF00483 NTP_transferase, 1 hit
SUPFAMiSSF53448 SSF53448, 4 hits

Sequencei

Sequence statusi: Complete.

A5PJI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE
60 70 80 90 100
VIVITTKDVQ KALCADFNKM KMKLDIVCIP DEADMGTADS LRHIYQKLKT
110 120 130 140 150
DVLVLSCDLI TDVALHEVVD LFRAHDASLA MLMRKGQESL EPVPGQKGKK
160 170 180 190 200
KAVEQRDFVG VDSTGKRLLF MANEADLDEE LIIKGSILQK HPRIRFHTGL
210 220 230 240 250
VDAHLYCLKK YVVDFLMENK SITSIRSELI PYLVRKQFSS ASSQQGQEEK
260 270 280 290 300
EEDLKKKELK SLDIYSFIKE ANTLTLAPYD TCWNACRGDS WEGLSRSQVR
310 320 330 340 350
CYVHIMKEGL CSRVSTLGLY MEANRQVSKL LPVICPEESL IHSSAQIVSK
360 370 380 390 400
HMVGADSLIG PDTQVGEKSS IKHSVIGSSC VIRDRVTVTN CLLMNSVTVE
410 420 430 440 450
EGSNIQSSII CNDAVIEKGA DIKNCLIGSG QRIEAKAKRV NVIVGNDQFL

EI
Length:452
Mass (Da):50,218
Last modified:July 10, 2007 - v1
Checksum:iA58454090E7F0623
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142127 mRNA Translation: AAI42128.1
UniGeneiBt.10192

Entry informationi

Entry nameiEI2BG_BOVIN
AccessioniPrimary (citable) accession number: A5PJI7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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