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A5PAC6 (A5PAC6_9SPHN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031
EC=3.6.4.12 HAMAP-Rule MF_00031
Gene names
Name:ruvA HAMAP-Rule MF_00031
ORF Names:ED21_20914 EMBL EDL49181.1
OrganismErythrobacter sp. SD-21 EMBL EDL49181.1
Taxonomic identifier161528 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length201 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031 SAAS SAAS011114

Catalytic activity

ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031 SAAS SAAS011114

Subunit structure

Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031 SAAS SAAS011114

Sequence similarities

Belongs to the RuvA family. HAMAP-Rule MF_00031

Sequences

Sequence LengthMass (Da)Tools
A5PAC6 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 02F835B460263F23

FASTA20120,088
        10         20         30         40         50         60 
MIAKLKGLLD ETGADWAVID VSGVGYLVHC STKTLSKLGE KGEACTVYTD LQVSENDMRL 

        70         80         90        100        110        120 
LGFAEAAERD WFRLLTQVQG VGSKVALAIL SALSTGEVQQ ACSNGDAATV ARAQGVGPKL 

       130        140        150        160        170        180 
AGRIVNELKD KAGALPGGGV GGGTAPATPA GGASADAVSA LENLGFKPAV AARAVAAAQG 

       190        200 
ELGEGASEGD LIRVALKRAA G

« Hide

References

[1]Tebo B., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SD-21 EMBL EDL49181.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		ABCG01000003 Genomic DNA. Translation: EDL49181.1.

3D structure databases

ProteinModelPortalA5PAC6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEDL49181; EDL49181; ED21_20914.
PATRIC30321821. VBIErySp11529_1344.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00031. DNA_helic_RuvA.
InterProIPR011114. DNA_helicas_Holl-junc_RuvA_C.
IPR013849. DNA_helicase_Holl-junc_RuvA_I.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR012340. NA-bd_OB-fold.
IPR000085. RuvA.
IPR010994. RuvA_2-like.
[Graphical view]
PfamPF07499. RuvA_C. 1 hit.
PF01330. RuvA_N. 1 hit.
[Graphical view]
SMARTSM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF47781. RuvA_2_like. 1 hit.
SSF46929. RuvA_C-like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5PAC6_9SPHN
AccessionPrimary (citable) accession number: A5PAC6
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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