A5N878 (A5N878_CLOK5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838
EC=2.4.2.11 RuleBase RU003838

Gene names

Ordered Locus Names:

CKL_1467 EMBL EDK33509.1

Organism

Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP] EMBL EDK33509.1

Taxonomic identifier

431943 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium kluyveri

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. SAAS SAAS007229 Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. RuleBase RU003838 SAAS SAAS007229
Sequence similarities	Belongs to the NAPRTase family. RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis RuleBase RU003838 SAAS SAAS007229
Molecular function	Glycosyltransferase RuleBase RU003838 SAAS SAAS007229 EMBL EDK33509.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	NAD biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway nicotinate nucleotide salvage Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5N878 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: BD9B25D09DB8B420	FASTA	493	56,030
	10 20 30 40 50 60 MENAKNFDVR NGRNLTMLVD FYEFTMNNGY FENNIGTKIA YFDMFFRSVP DGGGYCIMAG 70 80 90 100 110 120 VQQVIEYLSN LKFTKDDIEY LRSKKQFSEN FLNYLENFEF CCDVWAIPEG TPVFPNEPLL 130 140 150 160 170 180 TVRGPAIQAQ FIETMILLTI NHQTLIATKA SRICKAASGK PVMEFGSRRA QGYDGAVYGA 190 200 210 220 230 240 RAAVIGGCSS TACTIAEQMF GIPAVGTMAH SWIQLFPSEY ESFQAWAKVY PDNCILLIDT 250 260 270 280 290 300 YNVLKSGLPN AIKVFKEILI PNGYKPKGIR IDSGDITYLT KKCRKILDEA GLEDVDIVIS 310 320 330 340 350 360 NSLDEFIIRD VLSQGACIDS FGVGERLITA KSEPVFGGVY KLVAVEGEDK NIIPKIKISE 370 380 390 400 410 420 NEEKITNPGF KKIYRIFSKK EDKAVGDLIA LSNENINIGE PIELFDPTFT WKKKRLKNYY 430 440 450 460 470 480 AKELLVKIFD KGKLVYESPD VMDIRNKAQE EITKFWPEVL RFENPHHYYV DLSQNLWNLK 490 QQLLHKYSAT YEE

References

[1]

"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features." Seedorf H., Fricke W.F., Veith B., Bruggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G. Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8527 / DSM 555 / NCIMB 10680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000673 Genomic DNA. Translation: EDK33509.1.
RefSeq	YP_001394857.1. NC_009706.1.
3D structure databases
ProteinModelPortal	A5N878.
ModBase	Search...
Protein-protein interaction databases
STRING	431943.CKL_1467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EDK33509; EDK33509; CKL_1467.
GeneID	5394200.
KEGG	ckl:CKL_1467.
PATRIC	19464395. VBICloKlu111549_1532.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1488.
HOGENOM	HOG000001112.
KO	K00763.
OMA	PDNGSFV.
ProtClustDB	PRK09243.
Enzyme and pathway databases
BioCyc	CKLU431943:GJF1-1467-MONOMER.
UniPathway	UPA00253; UER00457.
Family and domain databases
InterPro	IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR006405. Nic_PRibTrfase_put. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
PANTHER	PTHR11098:SF1. PTHR11098:SF1. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01513. NAPRTase_put. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5N878_CLOK5

Accession

Primary (citable) accession number: A5N878

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)