ID   ACKA_CLOK5              Reviewed;         405 AA.
AC   A5N802;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA; OrderedLocusNames=CKL_1391;
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the acetokinase family.
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DR   EMBL; CP000673; EDK33433.1; -; Genomic_DNA.
DR   RefSeq; YP_001394781.1; -.
DR   GeneID; 5392221; -.
DR   GenomeReviews; CP000673_GR; CKL_1391.
DR   KEGG; ckl:CKL_1391; -.
DR   NMPDR; fig|431943.4.peg.1437; -.
DR   OMA; A5N802; SSDFRDV.
DR   BioCyc; MetaCyc:MON-13473; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:HAMAP.
DR   HAMAP; MF_00020; -; 1.
DR   InterPro; IPR000890; Acetate_kin.
DR   InterPro; IPR004372; AckA.
DR   PANTHER; PTHR21060; Acetate_kin; 1.
DR   PANTHER; PTHR21060:SF11; AckA; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    405       Acetate kinase.
FT                                /FTId=PRO_1000074184.
SQ   SEQUENCE   405 AA;  44449 MW;  468BDCF12E8C5C07 CRC64;
     MKILEVNCGS SSLKYQLIDM EDEKVLAKGL VERIGIDGSI LTHKVNGEKH VVSEPIKDHR
     VAVKLVLEAL VDKQHGVIKD MSEISAVGHR VVHGGEQYSD AVIIDDKVME SLKDCSKLAP
     LHNPPNIIGI NACKAIMPNT PMVAVFDTAF HHTMPKYAYI YPLPYELYER YGIRKYGFHG
     TSHRFVSEEA ARLMGKDISE LKIITCHLGN GASICAVDRG KSIDTNMGFT PLAGLAMGTR
     CGDIDPAIIP FLTNEIGMSI DEISNIMNNK SGILGMSGIS SDFRDVEEIA SFKHDRRAQL
     ALDVFYYRVK SFIGSYVAVL DGVDAIVFTA GVGENSSIGR AEICSGLTYL GITIDEEKNN
     IRGKATEITT ANSKTKVFVI PTNEELVIAR DTKFLVQKKI SHKSK
//