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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi39Divalent metal cationUniRule annotation1
Metal bindingi97Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:CKL_0997
OrganismiClostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
Taxonomic identifieri431943 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000002411 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000750221 – 2455'-nucleotidase SurEAdd BLAST245

Interactioni

Protein-protein interaction databases

STRINGi431943.CKL_0997.

Structurei

3D structure databases

ProteinModelPortaliA5N6V8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiDCVHIAL.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A5N6V8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLLTNDDG IMAEGIQVLA KHFEKDNEVI IAAPDVQRSG SGHCITTVPG
60 70 80 90 100
ELIIQEVKLE GINSKAYSIT GTPADCARLG VRKLGNNQID MVISGINNGF
110 120 130 140 150
NLGIDSLYSG TVSAAIEAAI CETPSIAVSL DTKGGNYDYN IAAEYALEVF
160 170 180 190 200
SIYKDKYKNK DENVVLSLNV PCLPREKIKG LKVCRVGFKY HLQEIYDKGE
210 220 230 240
KTEELSYNYT DIYYVKRGYA ALSPLHYDLT NYKILGDINN LFTEK
Length:245
Mass (Da):27,106
Last modified:July 10, 2007 - v1
Checksum:i9D27ABDB80351083
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000673 Genomic DNA. Translation: EDK33039.1.
RefSeqiWP_012101369.1. NC_009706.1.

Genome annotation databases

EnsemblBacteriaiEDK33039; EDK33039; CKL_0997.
KEGGickl:CKL_0997.

Similar proteinsi

Entry informationi

Entry nameiSURE_CLOK5
AccessioniPrimary (citable) accession number: A5N6V8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 10, 2007
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families