A5N6B2 (A5N6B2_CLOK5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AroE1 EMBL EDK32843.1
EC=1.1.1.25 EMBL EDK32843.1

Gene names

Name:	aroE1 EMBL EDK32843.1
Ordered Locus Names:	CKL_0790

Organism

Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP]

Taxonomic identifier

431943 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. SAAS SAAS011342

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342
Ligand	NADP SAAS SAAS011342
Molecular function	Oxidoreductase RuleBase RU004037 SAAS SAAS011342 EMBL EDK32843.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5N6B2 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: B636C9C084368502	FASTA	269	30,064
	10 20 30 40 50 60 MGNFYGLIGD KLGHSFSPVI HEMILKKINL QGKYNLFEIE SQNLGEAIGA LKILGCRGVN 70 80 90 100 110 120 VTIPYKIKIM KYMDYISEEA LSIGSINTIQ FVDNKLKAYN TDYYGFGMTL KRYGIDVLNK 130 140 150 160 170 180 SVVILGTGGA SKAVLRYSMD EGAKSIIYVS RKPENVSNGE IDVISYEQLH HIKSGDIIIN 190 200 210 220 230 240 STPCGMYPQT DTCAVDSEIL SKFNTAVDLV YNPQETTFLK TGKELGLRTA NGLYMLVAQA 250 260 VAAQQIWQHR EISLKTLDEI YYKLLNMQQ

References

[1]

"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features." Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G. Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed: 18218779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000673 Genomic DNA. Translation: EDK32843.1.
RefSeq	YP_001394191.1. NC_009706.1.
3D structure databases
ProteinModelPortal	A5N6B2.
ModBase	Search...
Protein-protein interaction databases
STRING	A5N6B2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5393617.
GenomeReviews	Gene locus CKL_0790 in contig CP000673_GR.
KEGG	ckl:CKL_0790.
NMPDR	fig|431943.4.peg.827.
PATRIC	19463017. VBICloKlu111549_0854.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0169.
HOGENOM	HBG553408.
OMA	TDYYGFG.
ProtClustDB	CLSK2319795.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5N6B2_CLOK5

Accession

Primary (citable) accession number: A5N6B2

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)