ID   A5N4K2_CLOK5            Unreviewed;       795 AA.
AC   A5N4K2;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Predicted stage II sporulation protein E {ECO:0000313|EMBL:EDK32233.1};
GN   OrderedLocusNames=CKL_0169 {ECO:0000313|EMBL:EDK32233.1};
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK32233.1, ECO:0000313|Proteomes:UP000002411};
RN   [1] {ECO:0000313|EMBL:EDK32233.1, ECO:0000313|Proteomes:UP000002411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC   {ECO:0000313|Proteomes:UP000002411};
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
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DR   EMBL; CP000673; EDK32233.1; -; Genomic_DNA.
DR   RefSeq; WP_011988759.1; NC_009706.1.
DR   AlphaFoldDB; A5N4K2; -.
DR   STRING; 431943.CKL_0169; -.
DR   KEGG; ckl:CKL_0169; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_017349_1_0_9; -.
DR   Proteomes; UP000002411; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014221; SpoII_E.
DR   InterPro; IPR045768; SpoIIE_N.
DR   NCBIfam; TIGR02865; spore_II_E; 1.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002411};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        213..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          580..791
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   795 AA;  89831 MW;  892B7C4D7ED47D27 CRC64;
     MQYGVEVVTY QRTEKLKGEE KKRKFEQMRN IVKLIFYFLC GFLVSRVMMV NLMAPFGIAF
     FISMALCEKR KPALVTGIGT LLGYISIYGN IKYLPSYCIV TVTLVTLNYI LKNSTKVKKL
     ILFFVITFLE FSAYKFFAIN LSPGVAILNS MFEIMCIFPL YFIINYSIIC FNQLKTRHLY
     SSEEIISMSI TTSLIIAGTW GTAIQGVSIR NVVALTFILI LGYVKGSASG AAGGVAMGTI
     IGVTSNDMMT YVSVYGLCGL ISGLFRETGK WMSGAGYIIG FAVLKMYSNI GSQFKIIEVL
     ISCIIYFGIP QSIYRKVELE LDWQKKQEHL KENYADKIKS IFMHRLDSFS HVLNDISSVL
     SRLASNNKLT MKTKSSALIE NLADRVCSNC DMNNMCWKRE TFYTYNAFLE LIQNYQENKK
     FIPEELQKKC TRRTLLLKNT KEIVNNYIVD EMWKSRLSEC RELLAYQIGN MGKTVGEIVQ
     DLNLDVRFNT SVENNIRRLL NKNNIKYKDV FCFKDKNEHL VINLSMEVCG GKQDCVKKIL
     PLINNVTGKL MALSKDSCDI NFSANSCSVT FEETPKYHIV THVISQCKHG EKYNGDSYSF
     CKLPDGTYMT IISDGMGSGP QAGEESSAAV ELIEKFAKSG FNKMTAINTV NSIMGIKFTE
     DEKFSTLDLS SINLYKGEID FMKVGATASF IKRGEDILVI KSKTLPIGIL DKPDIDIINK
     SVMNGDFIIM VSDGVIDYNS ESAGNFIWMI EFLRKLDCTE PKDMCEKIMD KSKELSGGKV
     KDDMTVIVEK VYTLY
//