Reviewed, UniProtKB/Swiss-Prot A5N4H7 (COMB_CLOK5)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CKL_0138

Organism

Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP]

Taxonomic identifier

431943 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000081393

Sequences

	Sequence		Length	Mass (Da)
	A5N4H7-1 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 27B317B9BBA406FB	FASTA	240	27,104
	10 20 30 40 50 60 MKIDIIISAD DIKKEKILHK SVIVVDMLRA TSVIITAINN GCREVIPVLT IEEALEIYHK 70 80 90 100 110 120 NREKYVMGGE RKALKIEGFH CSNSPLEYSR QVVENKTLVI TTSNGTKAIK GSIMAKNILI 130 140 150 160 170 180 GALINADEVA NRSINLNNDV VIVNAGTCGQ FSIDDFICSG YMINCVIKKI KVDLTDIART 190 200 210 220 230 240 ALYIYEQNPD IITFIKKASH YKRIKKLKLY DDLEYCCRKD IIKIVPEYID GIIKCNKLIY

References

[1]

"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features." Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G. Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed: 18218779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000673 Genomic DNA. Translation: EDK32208.1.
RefSeq	YP_001393556.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5392725.
GenomeReviews	Gene locus CKL_0138 in contig CP000673_GR.
KEGG	ckl:CKL_0138.
NMPDR	fig|431943.4.peg.190.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A5N4H7. DFICSGY.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_CLOK5

Accession

Primary (citable) accession number: A5N4H7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	July 10, 2007
Last modified:	May 5, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)