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A5N262 (A5N262_CLOK5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase 2 HAMAP MF_00102
Short name=DHPR 2 HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB2 HAMAP MF_00102 EMBL EDK35208.1
Ordered Locus Names:CKL_3205
OrganismClostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP]
Taxonomic identifier431943 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 SAAS SAAS022664

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 SAAS SAAS022664

Subcellular location

Cytoplasm By similarity HAMAP MF_00102 SAAS SAAS022664.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A5N262 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: D7E34BBC49AE3ABA

FASTA25027,541
        10         20         30         40         50         60 
MIRIILSGCN GKMGKVVTNL AESYSSLAIV AGVDKNCVKS KFPVFSDITK CNIEGDVILD 

        70         80         90        100        110        120 
FSRPEALDSI LKYAKEKNIG VILCTTGYSE EQLEKINEAS KYIPMFRSAN MSIGVNMVNK 

       130        140        150        160        170        180 
ILKNMSAVLY KNFDIEIIEK HHNQKVDSPS GTALLLGNTI KDSIEEKLDF VNGREGIKKR 

       190        200        210        220        230        240 
THNEIGIHAI RGGSIVGEHD VIFAGQGETI EIKHTAISRE VFAVGALKAC EFMFNREKGF 

       250 
YSMDDVIGGK

« Hide

References

[1]"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features."
Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G.
Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed: 18218779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000673 Genomic DNA. Translation: EDK35208.1.
RefSeqYP_001396579.1. NC_009706.1.

3D structure databases

ProteinModelPortalA5N262.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5N262.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5393975.
GenomeReviewsGene locus CKL_3205 in contig CP000673_GR.
KEGGckl:CKL_3205.
NMPDRfig|431943.4.peg.3231.
PATRIC19467962. VBICloKlu111549_3306.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0289.
HOGENOMHBG594002.
OMAMVRVILN.
ProtClustDBPRK00048.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5N262_CLOK5
AccessionPrimary (citable) accession number: A5N262
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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