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Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processSporulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
Ordered Locus Names:CKL_3155
OrganismiClostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
Taxonomic identifieri431943 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000002411 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001308101 – 142Anti-sigma F factorAdd BLAST142

Interactioni

Protein-protein interaction databases

STRINGi431943.CKL_3155

Structurei

3D structure databases

ProteinModelPortaliA5N217
SMRiA5N217
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZBE Bacteria
COG2172 LUCA
HOGENOMiHOG000269931
KOiK06379
OMAiHAYEDKI
OrthoDBiPOG091H0LCB

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.565.10, 1 hit
HAMAPiMF_00637 Anti_sigma_F, 1 hit
InterProiView protein in InterPro
IPR010194 Anti-sigma_F
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
PANTHERiPTHR35526:SF2 PTHR35526:SF2, 1 hit
PfamiView protein in Pfam
PF13581 HATPase_c_2, 1 hit
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF55874 SSF55874, 1 hit
TIGRFAMsiTIGR01925 spIIAB, 1 hit

Sequencei

Sequence statusi: Complete.

A5N217-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYDNSMKIEF ISKSQNESFA RVSVAAFVSQ LDPTLDELTD VKTAVSEAVT
60 70 80 90 100
NSIIHGYENK EGIVKIEASI KGRELILIVE DNGIGIENID MAMQPLYTSK
110 120 130 140
PELERSGMGF TVMETFMDSL QVESEKNKGT RLIMKKVFNS LS
Length:142
Mass (Da):15,833
Last modified:July 10, 2007 - v1
Checksum:iA2EE5BC473A23F99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000673 Genomic DNA Translation: EDK35163.1
RefSeqiWP_012103498.1, NC_009706.1

Genome annotation databases

EnsemblBacteriaiEDK35163; EDK35163; CKL_3155
KEGGickl:CKL_3155

Similar proteinsi

Entry informationi

Entry nameiSP2AB_CLOK5
AccessioniPrimary (citable) accession number: A5N217
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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