Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5N1D1 (A5N1D1_CLOK5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
Name:aroH EMBL EDK34927.1
Ordered Locus Names:CKL_2916
OrganismClostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP]
Taxonomic identifier431943 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Sequences

Sequence LengthMass (Da)Tools
A5N1D1 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 4FF526A88BC79557

FASTA34239,120
        10         20         30         40         50         60 
MSMKFIKKMP TAEEIIEEMP LSKHLKEVKK NRDEEIKKVF SNESSKFLLI IGPCSADNED 

        70         80         90        100        110        120 
SVCEYIGKLA GVQEKVKDVI IIIPRIYTNK PRTTGEGYKG MAHQPDLNKK PDLIAGIKAI 

       130        140        150        160        170        180 
RKMHIKSLSE YHMPAADEML YPENYTYLAD LLSYHAIGAR SVEDQQHRFT VSGIDMPVGM 

       190        200        210        220        230        240 
KNPTSGDLTV MLNSIKAAQL HHTFIYNGWE IETSGNPMAH AVLRGAVDSY GRNIPNYHYE 

       250        260        270        280        290        300 
NLVILSRRYE EKQLLNPSII IDTNHANSMK RYKEQPRIAR EVLMSRKYDT SLKHMIKGFM 

       310        320        330        340 
IESYLVEGNQ HIDEGVYGKS ITDPCLGWQD TEKLIYYIAE NM

« Hide

References

[1]"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features."
Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G.
Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed: 18218779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000673 Genomic DNA. Translation: EDK34927.1.
RefSeqYP_001396298.1. NC_009706.1.

3D structure databases

ProteinModelPortalA5N1D1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5N1D1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5393241.
GenomeReviewsGene locus CKL_2916 in contig CP000673_GR.
KEGGckl:CKL_2916.
NMPDRfig|431943.4.peg.2959.
PATRIC19467381. VBICloKlu111549_3024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0722.
HOGENOMHBG670536.
OMARGNRYGH.
ProtClustDBPRK09261.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01626.
PANTHERPTHR21225. AroFGH. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. AroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5N1D1_CLOK5
AccessionPrimary (citable) accession number: A5N1D1
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info