ID   DEOC_CLOK5              Reviewed;         218 AA.
AC   A5N0Z3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Deoxyribose-phosphate aldolase;
DE            EC=4.1.2.4;
DE   AltName: Full=Phosphodeoxyriboaldolase;
DE            Short=Deoxyriboaldolase;
DE            Short=DERA;
GN   Name=deoC; OrderedLocusNames=CKL_2777;
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-
CC       glyceraldehyde 3-phosphate + acetaldehyde.
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-D-ribose 1-phosphate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the deoC/fbaB aldolase family. DeoC type 1
CC       subfamily.
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DR   EMBL; CP000673; EDK34789.1; -; Genomic_DNA.
DR   RefSeq; YP_001396160.1; -.
DR   GeneID; 5392484; -.
DR   GenomeReviews; CP000673_GR; CKL_2777.
DR   KEGG; ckl:CKL_2777; -.
DR   NMPDR; fig|431943.4.peg.2826; -.
DR   OMA; A5N0Z3; AKMIDHT.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:HAMAP.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:HAMAP.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   HAMAP; MF_00114; -; 1.
DR   InterPro; IPR011343; DeoC.
DR   InterPro; IPR002915; DeoC/AroFGH_arch.
DR   PANTHER; PTHR10889; DeoC; 1.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF001357; DeoC; 1.
DR   TIGRFAMs; TIGR00126; deoC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Schiff base.
FT   CHAIN         1    218       Deoxyribose-phosphate aldolase.
FT                                /FTId=PRO_1000076028.
FT   ACT_SITE    155    155       Schiff-base intermediate with
FT                                acetaldehyde (By similarity).
FT   ACT_SITE    184    184       By similarity.
SQ   SEQUENCE   218 AA;  23545 MW;  A47504B5AB52B1CB CRC64;
     MDKKELAKMI DHTLLKPEAN YEQIVKLCKE ALEYGFASVC INPCYVNAAY QLLKGSDVKV
     CTVVGFPLGA ATSETKTFEA VQAVNRGASE IDMVINVGYL KSGNHDYVEE DIKTLVNKIN
     GRALVKVIIE TCLLNDEEKI IACKLAKKAG AHFVKTSTGF NMSGATSEDV ALMYDAVSPN
     LKVKASGGIR TYEDAIKMIN AGASRIGASS SIKIINKK
//