A5MHU9 (A5MHU9_STRPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL EDK67842.1

Gene names

ORF Names:

CGSSp18BS74_10839 EMBL EDK67842.1, CGSSp18BS74_11326 EMBL EDK67577.1

Organism

Streptococcus pneumoniae SP18-BS74 EMBL EDK67842.1

Taxonomic identifier

406561 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the dihydrofolate reductase family. RuleBase RU004474
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EDK67842.1

Ontologies

Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5MHU9 [UniParc]. Last modified July 10, 2007. Version 1. Checksum: 4C3887E290B6303E	FASTA	168	19,703
	10 20 30 40 50 60 MTKKIVAIWA QDEEGVIGKE NRLPWHLPAE LQHFKETTLN HAILMGRVTF DGMGRRLLPK 70 80 90 100 110 120 RETLILTRNP EEKIDGVATF QDVQSVLDWY QAQEKNLYII GGKQIFQAFE PYLDEVIVTH 130 140 150 160 IHARVEGDTY FPEELDLSLF ETVSSKFYAK DEKNPYDFTI QYRKRKEV

References

[1]

"Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome." Hiller N.L., Janto B., Hogg J.S., Boissy R., Yu S., Powell E., Keefe R., Ehrlich N.E., Shen K., Hayes J., Barbadora K., Klimke W., Dernovoy D., Tatusova T., Parkhill J., Bentley S.D., Post J.C., Ehrlich G.D., Hu F.Z. J. Bacteriol. 189:8186-8195(2007) [PubMed: 17675389] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SP18-BS74 EMBL EDK67842.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABAE01000015 Genomic DNA. Translation: EDK67577.1. ABAE01000011 Genomic DNA. Translation: EDK67842.1.
3D structure databases
ProteinModelPortal	A5MHU9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	28655071. VBIStrPne31255_1795.
Phylogenomic databases
OMA	QDEEGVI.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5MHU9_STRPN

Accession

Primary (citable) accession number: A5MHU9

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)